?cl25937: MT Superfamily (this model, PSSM-Id:330758 is obsolete)
Microtubule-binding stalk of dynein motor the 380 kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases. The core of the 380 kDa motor unit contains a concatenated chain of six AAA modules, of which four correspond to the ATP binding sites with P-loop signatures described previously, and two are modules in which the P loop has been lost in evolution. This family is the region between D4 and D5 and is the two predicted alpha-helical coiled coil segments that form the stalk supporting the ATP-sensitive microtubule binding component. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",