4CPG


Conserved Protein Domain Family
SGTA_dimer
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pfam16546: SGTA_dimer (this model, PSSM-Id:318697 is obsolete and has been replaced by 465168)
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Homodimerisation domain of SGTA
SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerisation domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerisation domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.
Links
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Statistics
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PSSM-Id: 318697
Aligned: 87 rows
Threshold Bit Score: 61.7615
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4CPG_A        19 KRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLAL------PQTLPEIFEA 78  human
Q21746        24 QNLVVSFLQFIRQKVSQNQATAEQAEALEVAIQCLEHSFGLDDASYAFQP------SRPILELFKS 83  Caenorhabditis elegans
Q28H19         5 KRLAFSIIRHLHDQLRNGGLSSDAQESLEVAIQCLETAFEVSIEDSNLAV------PRSLQEIFTE 64  tropical clawed frog
XP_002591391   7 gKMVFAIIDFLNDQLHSGQLSGDAAESLEVAIQCLETAYGIEYKDAACVArlh-tkP-PLYELFls 70  Florida lancelet
XP_786841      5 NRLVFAIVEFLDQQVRSNAVSGEALESLEVGLQCLQTAYGISLDDPALTSqk---tERSLLEIFTS 67  purple sea urchin
XP_002172748   5 NKFALSIIDFLQVSAANEHLAKNKQECLEVAAQCLADAFDLDKKDAPSGA------GAKLKTAFEE 64  Schizosaccharomyces japonicus...
XP_003387439  16 sKAAYTVLRFIGDSIKDDSTSDDSKESLEVAMECLQAVFGMNLDEAENNdty--kkLPSLQSLIEN 79  Amphimedon queenslandica
KKA66683      45 KNLAVSFIQFIRHKVSANQCTDDQIEALEVAVQCLESAFALTDANYAFQP------SKSLLALFTA 104 Pristionchus pacificus
XP_002404605   5 KRLVLSIVQFLRQQLQTADLSSDAKESVEVAVQCLETAYGVSIDDLSNDSll---vSRTLLDIFRE 67  black-legged tick
Q1HQM2         7 KFFVRSFIRFLNGQLEQPNFSSDSRESLEVAIQCLENVYEIGQEAEGDNSqenplnHIDLFEVYRS 72  yellow fever mosquito
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