Conserved Protein Domain Family
COR
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pfam16095: COR (this model, PSSM-Id:318343 is obsolete and has been replaced by 406489)
C-terminal of Roc, COR, domain
The C-terminal of Roc domain, COR, along with Roc functions as the putative regulator of kinase activity. It functions as a proper GTP-binding protein with a low GTPase activity somehow stimulating the kinase activity.
Links
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Statistics
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PSSM-Id: 318343
Aligned: 47 rows
Threshold Bit Score: 151.963
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q55E58       1918 PRSYMLLENLVKEet----kKR--I--I--PTIPWTEFIQMGTICTITDEAELLRATMFLHQLGSLVYF-----PK-E-- 1979 Dictyostelium...
EKC19720     2667 PQVWLNLEDKMIKm------RK--E--N--AILDWGEVEKIAREEGIYHEQDLKEAVSFLDNLGTVQYF-----DT-D-- 2726 Pacific oyster
EKC33500     2508 PQVWLNLEKQILAe------RT--K--Q--SILDYSVIEDFAMEHGIFDDKDVKQAIKFLDDLGTVQYF-----DN-D-- 2567 Pacific oyster
EFA78013      515 PSSYLLLENLVKEe------RRvrT--I--PTMSWAEFVQLGKLCTINDEDELVRATIFLNQIGSLVYF-----PN-E-- 576  Polysphondyli...
EKC18603     1839 PMAWLELEEIIKKl------KT--KtkM--DTIEYSQLFKRAGVAGIVNEKEFAEAVAFLHDLGSLQHF-----SG-N-- 1900 Pacific oyster
WP_049875725  201 PRAWLRAADTVRAa------ED--K------HITPEKLNELLATAGVREPSHQTSLIAALHSLGDLLYY-----PD-D-- 258  Streptomyces ...
XP_002113972 1959 PNIWLEYENSIISc------RN--R--S--SVLSWKEITEIACNHGIFQDDEIREAVKLLTDLGSIQHF------D-T-- 2017 Trichoplax ad...
EFA81294     1147 PIPFVLLRNQLIEtckdasrHS--R--I--PATSQAKIRSIAKSINLESRQ-IDDAMKYLLRCGDILYY-----RD-Dgd 1213 Polysphondyli...
XP_003290696  533 PSSFFTLEEALIEv------KK--K--RipPVMMWQEYINLANICNLKDSVQIQRATEFLHNIGSIVYF-----NDlN-- 595  Dictyostelium...
XP_004352372 1370 PIPYILLRNQLVEsanearrLS--K--L--PITSIARVRQISITLGLDAKQ-VDDALAYLCKTGDILMFnqeggDN-D-- 1439 Dictyostelium...

Q55E58       1980 PGLKQFVILDPQWITTMLSSIITTKHSY--Ak--dGILNHKSLKQIWRPPqYPTHLHPHLISLLEKFEISYN-LS----- 2049 Dictyostelium...
EKC19720     2727 -FLRDKVVVDPQWIVNVMACVVSVRASV--IqrndGRFEHSQLDTVW-EK-FAPDLRPWLLSLTEEFDLTYP-LP----- 2795 Pacific oyster
EKC33500     2568 -FLRDKVVINPQWIVNVMACVVSVKQSPiqNh--dGRFLHEHIKDVWKS--YDESLHNWLLSLTEEFDLTFP-LP----- 2636 Pacific oyster
EFA78013      577 EGLKKIVILDPQWITLMLASIITVKHNY--Tn--qGVILHRDLKHIWKAPfYPQELHPHLLTLLEKFEISFN-FQ----- 646  Polysphondyli...
EKC18603     1901 EYLHSKVVVNPQWIVDVMACVVSVKESP--Ik--nGRLKHEDAKKVWKD--YPESLHQWLLRLTEEFDLTFC-IP----- 1968 Pacific oyster
WP_049875725  259 EELCDLVVLRPQWLTTYISRVLDSEEVL--Ne--gGLFHRSLWATLWRD--VERSMRRHLSRMMENFDLSYR-TE----- 326  Streptomyces ...
XP_002113972 2018 EMLREVVVINPQWIVDVMACVVSVHDSP--Ik--nGRFHHSDMQKIWS-K-YNSNLHKWLLGLTEQFDLSFS-LP----- 2085 Trichoplax ad...
EFA81294     1214 NELNDIVFLEPLWLSRVLSTVTNLKHQn-------GYLLMGGINQAWDEK-YPRSIHTSLTHLLEQFEIMHSnTG----- 1280 Polysphondyli...
XP_003290696  596 SSVGKMVILDQQWIINCMSSLITSKVLI--Nnc-nGIVRQSDLELVWKAPtYPEHLHSALLSIMQAFEICRP-LS----- 666  Dictyostelium...
XP_004352372 1440 SVFTQLIFLDAAWLSKLVSSVFTLKHQn-------GMLLMDKIHQAWDHL-FLRQLQPSLLYLLENFEIMHS-SHsseeg 1510 Dictyostelium...

Q55E58       2050 ----Pdsts---------fetGTSLIPSLLLNDRPAifpslwg---sfnqlvrQF--------GRIYQFEFVPNGFFSRL 2105 Dictyostelium...
EKC19720     2796 ----Gq---------------QLNIVPCLLPLEPPEefqwpeld--rlddsvhEN--------KIVYRFVYLPGGLFNRL 2846 Pacific oyster
EKC33500     2637 ----Gk---------------PINIVPCLLPLEQPTelqwpav---dmehgirEN--------KMLYKFAYLPAGLFNRA 2686 Pacific oyster
EFA78013      647 ----Gktssgqlq-dvvhddnARSLIPALLSNECPSefgklwgsnrggvmaaiQY--------GRQYQFDFIPTGLFSRL 713  Polysphondyli...
EKC18603     1969 ----Qeeg----------skeRVNLVPCLLPESKPKfewpepd----kkngvtET--------KMVYMFDYLPAGLFNRG 2022 Pacific oyster
WP_049875725  327 ----Dq---------------TASLVVELLPWNPPPyqdewns---perlaqrEL--------RLKYRLHTVPPGIPTWF 376  Streptomyces ...
XP_002113972 2086 ----Nk---------------STNLVPCLLNDDDEEtddldket--lemdgmkET--------KMVYTFQYLPAGLFNRL 2136 Trichoplax ad...
EFA81294     1281 ----Gdn-------------gDSIIVPMLFSEERPVvmamlwp---efdhirqQH--------ERIYQFQFLPKGFFSRL 1332 Polysphondyli...
XP_003290696  667 ----PsdlvkpdeindkevigDRNLVPNLLSDNNSNiitqwdd---fidpdtiLL--------NRQYHLPFLPEKFFGKL 731  Dictyostelium...
XP_004352372 1511 pgsvEde-------------sYQIIVPLLFGEERPTvmpm----------lwpEFdhsrpvtqERIYQFKFLPKGFFSRL 1567 Dictyostelium...

Q55E58       2106 MVRILNFARVEakCYWKNGMIL 2127 Dictyostelium discoideum
EKC19720     2847 QVRLFNFSDGK--MIWKKGSFL 2866 Pacific oyster
EKC33500     2687 QVRLFNFSDGK--IIWKNGSYL 2706 Pacific oyster
EFA78013      714 MVRILNFASSEaiCYWRNGIIL 735  Polysphondylium pallidum PN500
EKC18603     2023 QVRLQEYSDYY--IIWKKGSFL 2042 Pacific oyster
WP_049875725  377 IAREHRFSTS---VRWRSGALV 395  Streptomyces scabiei
XP_002113972 2137 QVRLCEFTEDQ--TISKRGSKL 2156 Trichoplax adhaerens
EFA81294     1333 SVKMLQNFDPL--CIWQGGMVI 1352 Polysphondylium pallidum PN500
XP_003290696  732 IIHLMNFTKVE--SCYKRVVVV 751  Dictyostelium purpureum
XP_004352372 1568 SVRMLQNFDPL--AIWQSGMVI 1587 Dictyostelium fasciculatum
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