pfam04732: Filament_head (this model, PSSM-Id:309741 is obsolete and has been replaced by 461414)
Intermediate filament head (DNA binding) region
This family represents the N-terminal head region of intermediate filaments. Intermediate filament heads bind DNA. Vimentin heads are able to alter nuclear architecture and chromatin distribution, and the liberation of heads by HIV-1 protease liberates may play an important role in HIV-1 associated cytopathogenesis and carcinogenesis. Phosphorylation of the head region can affect filament stability. The head has been shown to interaction with the rod domain of the same protein.
Jiyao W et al.(2023). "The conserved domain database in 2023.",