4JA4_A 13 ITLVATLGG-LLFGYDTAVISGTVESLNtvfVAPQNLSESaANsl----------------lgFCVASALIGCIIGGALG 75 Escherichia coli K-12 P0C0L7 25 KAITAASLGnAMEWFDFGVYGFVAYALGkvfFPGADPSVQmVAa------------------lATFSVPFLIRPLGGLFF 86 Escherichia coli K-12 P36035 125 VNPIPELRKmTWQNWNYFFMGYFAWLSAawaFFCVSVSVApLAelydrp---------tkditWGLGLVLFVRSAGAVIF 195 Saccharomyces cerevis... P38142 27 GTIVACLGS-IQYGYHIAELNAPQEFLScsrFEAPDENISyDDtwvgqhglkqcialtdsqygAITSIFSIGGLFGSYYA 105 Saccharomyces cerevis... P22732 20 ATLIAAFGSsFQYGYNVAAVNSPALLMQqfyNETYYGRTGeFMedfpl----------tllwsVTVSMFPFGGFIGSLLV 89 human P38156 102 WSLLVSTTL-IQEGYDTAILGAFYALPVfqkKYGSLNSNTgDYeisv------------swqiGLCLCYMAGEIVGLQMT 168 Saccharomyces cerevis... P15325 24 LAAVASFTS-CMIGYDSAFIGTTLSLQSfqnEFNWESLNTdLIs------------------aNIVSLYQAGAFFGALFA 84 Aspergillus nidulans ... P11636 24 CAAIASFAS-CMIGYDSAFIGTTLALPSftkEFDFASYT--PGalal-------------lqsNIVSVYQAGAFFGCLFA 87 Neurospora crassa OR74A P07921 75 LCFITYLCA-TMQGYDGALMGSIYTEDAylkYYHLDINSSsGt-------------------gLVFSIFNVGQICGAFFV 134 Kluyveromyces lactis ... P25346 43 KNIVTIIASgFALISDGYVNGSMSMLNKvfvMEYGKKNYSsKVs------------------tRVSNAALVGIIFGQFFM 104 Saccharomyces cerevis...
4JA4_A 76 GYCSNRFGRRDSLKIAAVLFFISGVGSAWPElgftsinpdnTVPVYLAGyvpefviyRIIGGIGVGLASMLSPMYIAELA 155 Escherichia coli K-12 P0C0L7 87 GMLGDKYGRQKILAITIVIMSISTFCIGLIPsydt--igiwAPILLLIC--------KMAQGFSVGGEYTGASIFVAEYS 156 Escherichia coli K-12 P36035 196 GLWTDKSSRKWPYITCLFLFVIAQLCTPWCD-----------TYEKFLGv-------RWITGIAMGGIYGCASATAIEDA 257 Saccharomyces cerevis... P38142 106 GNWANRYGRKYVSMGASAMCMVSSLLLFFSN----------SYLQLLFG--------RFLVGMSCGTAIVITPLFINEIA 167 Saccharomyces cerevis... P22732 90 GPLVNKFGRKGALLFNNIFSIVPAILMGCSRva-------tSFELIIIS--------RLLVGICAGVSSNVVPMYLGELA 154 human P38156 169 GPSVDYMGNRYTLIMALFFLAAFIFILYFCK----------SLGMIAVG--------QALCGMPWGCFQCLTVSYASEIC 230 Saccharomyces cerevis... P15325 85 YPIGHFWGRRWGLMFSALIFFLGAGMMLGANgd-------rGLGLIYGG--------RVLAGIGVGAGSNICPIYISEMA 149 Aspergillus nidulans ... P11636 88 YATSYFLGRRKSLIAFSVVFIIGAAIMLAADgq------grGIDPIIAG--------RVLAGIGVGGASNMVPIYISELA 153 Neurospora crassa OR74A P07921 135 P-LMDWKGRKPAILIGCLGVVIGAIISSLTT----------TKSALIGG--------RWFVAFFATIANAAAPTYCAEVA 195 Kluyveromyces lactis ... P25346 105 GIAADYYSRKSCILVATAILVIGSALCAASHgtt----vpgMFWMLTVM--------RGLVGIGVGAEYPTSTLSANESA 172 Saccharomyces cerevis...
4JA4_A 156 ---PAHIR-GKLVSFNQFAIIFGQLLVYCVNYFI-ARSGDaswlntdgWRYMFASECIPALLFLMLLYTVPESPRWL-MS 229 Escherichia coli K-12 P0C0L7 157 ---PDRKR-GFMGSWLDFGSIAGFVLGAGVVVLI-STIVGeanfldwgWRIPFFIALPLGIIGLYLRHALEETPAFQ-QH 230 Escherichia coli K-12 P36035 258 ---PVKAR-SFLSGLFFSAYAMGFIFAIIFYRAF-GYFRDd------gWKILFWFSIFLPILLIFWRLLWPETKYFTkVL 326 Saccharomyces cerevis... P38142 168 ---PVEWR-GAMGSMNQVSINLGILLTQTLALKY-ADSYN--------WRWLLFSGSVIAVANILAWLKVDESPRWL-VS 233 Saccharomyces cerevis... P22732 155 ---PKNLR-GALGVVPQLFITVGILVAQIFGLRN-LLANVd------gWPILLGLTGVPAALQLLLLPFFPESPRYL-LI 222 human P38156 231 ---PLALR-YYLTTYSNLCWAFGQLFAAGIMKNSqNKYANse----lgYKLPFALQWIWPLPLAVGIFFAPESPWWL-VK 301 Saccharomyces cerevis... P15325 150 ---PPAIR-GRLVGVYELGWQIGGVVGFWINYGV-DETLApsh---kqWIIPFAVQLIPAGLLIIGALLIRESPRWL-FL 220 Aspergillus nidulans ... P11636 154 ---PPAVR-GRLVGIYELGWQIGGLVGFWINYGV-NTTMAptr---sqWLIPFAVQLIPAGLLFLGSFWIPESPRWL-YA 224 Neurospora crassa OR74A P07921 196 ---PAHLR-GKVAGLYNTLWSVGSIVAAFSTYGT-NKNFPnss---kaFKIPLYLQMMFPGLVCIFGWLIPESPRWL-VG 266 Kluyveromyces lactis ... P25346 173 neyTTTKRgGILVMVTNLPLAFGGPFATIIFLIVyKICSG-----------TKHLEAIWR-TVFAIGCFWPLSVFYF-RW 239 Saccharomyces cerevis...
4JA4_A 230 RGKQE-QAEGILRK---IMGN---TLATQAVQEIKHSLDHGRK----------TGGRLLMFGv----gVIVIGVMLSIFQ 288 Escherichia coli K-12 P0C0L7 231 VDKLEqGDREGLQD-----------GPKVSFKEIATKYWRS----------------------------LLTCIGLVIAT 271 Escherichia coli K-12 P36035 327 KARKLiLSDAVKAN----GGE---PLPKANFKQKMVSMKRT------------VQKYWLL---------FAYLVVLLVGP 378 Saccharomyces cerevis... P38142 234 HGFVS-EAETALFK---LRPGt-yQQAKQEIQDWQRSHGHNRDpesse-ethsGPTLWQYVTdpsykkPRTVILAILSCQ 307 Saccharomyces cerevis... P22732 223 QKKDEaAAKKALQT---LRGW---DSVDREVAEIRQEDEAEKAagf-----isVLKLFRMRSlr---wQLLSIIVLMGGQ 288 human P38156 302 KGRID-QARRSLERtlsGKGPekeLLVSMELDKIKTTIEKEQKmsde---gtyWDCVKDGINr----rRTRIACLCWIGQ 373 Saccharomyces cerevis... P15325 221 RGNRE-KGIETLAW---IRNL---PADHIYMVEEINMIEQSLEqqrvkiglgfWKPFKAAWTnkrilyRLFLGSMLFLWQ 293 Aspergillus nidulans ... P11636 225 NGKRE-EAMKVLCW---IRNL---EPTDRYIVQEVSFIDADLErytrqvgngfWKPFLSLKQrkv-qwRFFLGGMLFFWQ 296 Neurospora crassa OR74A P07921 267 VGREE-EAREFIIKy-hLNGDrthPLLDMEMAEIIESFHGTDLsnpl--emldVRSLFRTRSdr---yRAMLVILMAWFG 339 Kluyveromyces lactis ... P25346 240 KT----ATTEVYEK-----------GRIKRNIPYFLALKFY------------WKRLLGTCG---------TWFMYDFVT 283 Saccharomyces cerevis...
4JA4_A 289 QFVGINVVLYYAPEVFKTLGASTDi-aLLQTIIVGVINLTFTVLA-I--MTVDKFGRKPLQIIGALGMAIGMFSLG---- 360 Escherichia coli K-12 P0C0L7 272 NVTYYMLLTYMPSYLSHNLHYSEDhgvLIIIAIMIGMLFVQPVMG----LLSDRFGRRPFVLLGSVALFVLAIPA----- 342 Escherichia coli K-12 P36035 379 NYLTHASQDLLPTMLRAQLGLSKD----AVTVIVVVTNIGAICGGmIfgQFMEVTGRR-LGLLIACTMGGCFTYP----- 448 Saccharomyces cerevis... P38142 308 QFCGINSIIFYGVKVIGKILPDYS---IQVNFAISILNVVVTLAA-S--AIIDHVGRRPLLLASTTVMTAMSLLIS---- 377 Saccharomyces cerevis... P22732 289 QLSGVNAIYYYADQIYLSAGVPEEh-vQYVTAGTGAVNVVMTFCA-V--FVVELLGRRLLLLLGFSICLIACCVLTa--- 361 human P38156 374 CSCG-ASLIGYSTYFYEKAGVSTDt-aFTFSIIQYCLGIAATFIS-W--WASKYCGRFDLYAFGLAFQAIMFFIIG---- 444 Saccharomyces cerevis... P15325 294 NGSGINAINYYSPRVFKSIGVSGGntsLLTTGIFGVVKAVITFVWlL--YLIDHFGRRNLLLVGAAGGSVCLWIVGgy-- 369 Aspergillus nidulans ... P11636 297 NGSGINAINYYSPTVFRSIGITGTdtgFLTTGIFGVVKMVLTIIWlL--WLVDLVGRRRILFIGAAGGSLCMWFIGayik 374 Neurospora crassa OR74A P07921 340 QFSGNNVCSYYLPTMLRNVGMKSVslnVLMNGVYSIVTWISSICG-A--FFIDKIGRREGFLGSISGAALALTGLSi--- 413 Kluyveromyces lactis ... P25346 284 FPNGIFSSTIISSVIKDQNDLVKV---AEWNLLLGVLAVLGVPIG-A--YLSDRIGRKYTLMFGFSGYIIFGLIIGc--- 354 Saccharomyces cerevis...
4JA4_A 361 -TAFYTQAp---------GIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMD 430 Escherichia coli K-12 P0C0L7 343 -FILINSN----------VIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAAFNISVLVAGLTPTLAAWLV 411 Escherichia coli K-12 P36035 449 -AFMLRSE----------KAILGAGFMLYFCVFG-VWGILP-IHLAELAPADARALVAGLSYQLGNLASAAASTIETQLA 515 Saccharomyces cerevis... P38142 378 -VGLTLSV----------SFLLVTATFVYIAAFAIGLGPIPFLIIGELSYPQDAATAQSFGTVCNWLATFIVGYLFPIGH 446 Saccharomyces cerevis... P22732 362 -ALALQDTvs------wmPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQ 434 human P38156 445 -GLGCSDThg-------aKMGSGALLMVVAFFYNLGIAPVVFCLVSEIPSSRLRTKTIILARNAYNVIQVVVTVLIMYQL 516 Saccharomyces cerevis... P15325 370 iKIAKPENnpegtqldsgGIAAIFFFYLWTAFYTPSWNGTPWVINSEMFDPTVRSLAQACAAASNWLWNFLISRFTPQMF 449 Aspergillus nidulans ... P11636 375 iADPGSNKaedak-ltsgGIAAIFFFYLWTAFYTPSWNGTPWVINSEMFDQNTRSLGQASAAANNWFWNFIISRFTPQMF 453 Neurospora crassa OR74A P07921 414 cTARYEKTkkk-----saSNGALVFIYLFGGIFSFAFTPMQSMYSTEVSTNLTRSKAQLLNFVVSGVAQFVNQFATPKAM 488 Kluyveromyces lactis ... P25346 355 -AYDQLKKi---------TPLFIIFYAFMNMLGNAGPGDMLGVISSEASATAVRGVFYGLSAVTGKIGSVVGVECFQPIR 424 Saccharomyces cerevis...
4JA4_A 431 KNSWlvahfhnGFSYWIYGCMGVLAALFMWKFVPETKGKTLEELEALW 478 Escherichia coli K-12 P0C0L7 412 ESSQn------LMMPAYYLMVVAVVGLITGVTMKETANRPLKGATPAA 453 Escherichia coli K-12 P36035 516 DRYPlerdasgAVIKEDYAKVMAILTGSVFIFTFACVFVGHEKFHRDL 563 Saccharomyces cerevisiae S288c P38142 447 GLMG-------GYVFAIFAAIAAMFATYVYKRVPETKGKTT--YSEVW 485 Saccharomyces cerevisiae S288c P22732 435 EGLG-------PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475 human P38156 517 NSEKwn---wgAKSGFFWGGFCLATLAWAVVDLPETAGRTFIEINELF 561 Saccharomyces cerevisiae S288c P15325 450 TSMG-------YGVYFFFASLMILSIVFVFFLIPETKGVPLESMETLF 490 Aspergillus nidulans FGSC A4 P11636 454 IKME-------YGVYFFFASLMLLSIVFIYFFLPETKSIPLEAMDRLF 494 Neurospora crassa OR74A P07921 489 KNIK-------YWFYVFYVFFDIFEFIVIYFFFVETKGRSLEELEVVF 529 Kluyveromyces lactis NRRL Y-1140 P25346 425 DNLGa------RWTFIIAAICGLIGIIITYFFVPHSLESDLMKQDVEF 466 Saccharomyces cerevisiae S288c
Jiyao W et al.(2023). "The conserved domain database in 2023.",