Conserved Protein Domain Family
BRCT_2
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pfam16589: BRCT_2 (this model, PSSM-Id:293197 is obsolete and has been replaced by 465186)
BRCT domain, a BRCA1 C-terminus domain
This BRCT domain, a BRCA1 C-terminus region, is found on many RAP1 proteins, usually at the very N-terminus. The function in human at least of a BRCT is to contribute to the heterogeneity of the telomere DNA length, but that may not be its general function, which remains unknown.
Links
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Statistics
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PSSM-Id: 293197
Aligned: 52 rows
Threshold Bit Score: 48.7408
Created: 3-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q08CM6         45 IMTVFE---NCTVVFDVK-Nv-PfkEKQKLKSALLENGGNISYTINKECSFV--VTSHVNDLSSNRqrsiqklqipvVGT 117  zebrafish
KGQ99688       89 PKPIFVdkdGKSMLFYIP-EdeP--NRNKYRDLIIRYGGVIVEKGFPTVILL--SNNEDLYGFSK--------------L 149  Candida albic...
CCE44938      111 HAHIFVtsdNKPMPFFIP-FdeP--NRNKYKRMIMQNGGYLAEGEVDGIVCV--TSKSHLGGF--------------VRI 171  Candida parap...
EMG49340       72 PKTIFVdkdNKTMLFYIP-KeeP--NRIKYRELIIKHGGLLVDKQIPTAYHL--SNNEKMLGY--------------FKL 132  Candida malto...
XP_001525810   66 rNQIFVtrdGKPIAFYLG-FneP--NRAKYVTAIIENGGFITEGGVENVIYL--TSHTKDMG--GY-----------VRT 127  Lodderomyces ...
XP_003868950   94 QASIFVtsdNKPIPFFIP-FdeP--DRTKYRRMIIQNGGYLAEGGVENMIYV--TSKEHLGGF--------------VRI 154  Candida ortho...
XP_007374266   45 QRNLFIdrdGRSLLFYIP-RneP--HRSHYRQLIISYGGVVTDRLIPSCYFL--SNNAEEGH---G-----------IQL 105  Spathaspora p...
XP_002547686   70 PPPIFVtpdGRSMRFTIQ-HgeP--RRAEFVQKIITHGGAVIEPGKDVISLG--QQDAISLGQHGV-----------FSI 133  Candida tropi...
XP_001384938   41 KSTLFTnreGRSIRFYMEySe-P--RRLHYKALIETHGGVLLDHSVTDCFWL---STNPLTG-RRS-----------YRV 102  Scheffersomyc...
XP_012178299  337 dEEIFKtdaGDSMMFYVQ-Ie-Tr-NRGEVVQSIRKHGGKIVPDIPQADVVIlaQHTKPFSDWLRRaqqa---krptAQA 410  Fibroporia ra...

Q08CM6        118 QYVWSCVDEGHLLPLTEHN 136  zebrafish
KGQ99688      150 KFIDDCIAKNQLLSVFDYg 168  Candida albicans GC75
CCE44938      172 DYIDDCVSVGQLLPFEGYt 190  Candida parapsilosis
EMG49340      133 KFIDDCIANGGLVPLLDYg 151  Candida maltosa Xu316
XP_001525810  128 QFIDDCILAGTLLPSHNYV 146  Lodderomyces elongisporus NRRL YB-4239
XP_003868950  155 NYIDDCIGMGQLLPPGDYt 173  Candida orthopsilosis Co 90-125
XP_007374266  106 RFIDECINQGRLVNLDSFR 124  Spathaspora passalidarum NRRL Y-27907
XP_002547686  134 DFIDDCIEQGQIIAIAPYi 152  Candida tropicalis MYA-3404
XP_001384938  103 QYIDDCVRLVTLQDIRIYs 121  Scheffersomyces stipitis CBS 6054
XP_012178299  411 SYVHDCITEGSILDIEPYs 429  Fibroporia radiculosa
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