Conserved Protein Domain Family
PRKG1_interact
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pfam15898: PRKG1_interact (this model, PSSM-Id:292521 is obsolete and has been replaced by 464927)
cGMP-dependent protein kinase interacting domain
This domain is found at the C-terminus of protein phosphatase 1 regulatory subunits 12A, 12B and 12C. In protein phosphatase 1 regulatory subunit 12A it has been found to bind to cGMP-dependent protein kinase 1 via a leucine zipper motif located at the C-terminus of this domain.
Links
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Statistics
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PSSM-Id: 292521
Aligned: 44 rows
Threshold Bit Score: 53.3897
Created: 16-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q08BR9        572 DYRKLYLRVLQENGNLKEKLQETQLQLNESKVQLEKLK-Q---NQEn------------GSDRPALLEL-ERYEKKLLQR 634  zebrafish
GAA48994      185 DYKRLYEAEKLATDELRNEVMAAQKETRDLQERIEAAKqS---R-----------------------SM-SGAHQRKIER 237  Clonorchis si...
CDS26837      877 DYRMLYEEEKSEKEGLKRTLEQLSQEIHMLRSELAKLHvS---NSN-------------PTNATS--------PKSSVDS 932  Hymenolepis m...
CCD81192      108 NYKQLYEEEKILTNGLREEVKAAQKELKELEDALENSVgR---RRP------------------------SEVEQRKMER 160  Schistosoma m...
XP_002629661  909 NYKALFEKERTECERLRREMDDMRRSQTIEPWRGSSSTqSpawRTRgaspsattiqnlsVAKSTSLASF-DENERRSMER 987  Caenorhabditi...
EJW81151      292 DYKALYEKEKQETERLRHQIEELSLEKSNSANSIPLLKcNiggRLTsl---------psLNKSSSSVSM-NDRERHSYEQ 361  Wuchereria ba...
XP_003091691 1048 NYKALFEKERTECDRLRREMDDLRRSQTNDTWRGAST--QpawRTRnaspsa-qphnlsVAKSTSLASF-DENERRSMER 1123 Caenorhabditi...
CDJ06265      765 DYRLLYEEERSEKERLKRTLDQVNREVAALRSELARLHvS-------------------NSASATLTANrRGSSASNTDA 825  Echinococcus ...
GAA50590      830 DYRRLYEAEKAEKDRLMRELDRITKENANLRLQLTRLNkEd-----------------------------SRSGVNSLNS 880  Clonorchis si...
CCD59362      995 DYKRLYEREKEERERLQRELDKCNRQISQLRQ--------------------------------------EQQLRSSNDH 1036 Schistosoma m...

Q08BR9        635 RAF---E------L-------EDEL--------KVLVDLRADNQRLKDENAALIRVISKL 670  zebrafish
GAA48994      238 RIS---E------C-------EEEL--------KTLEKLRAESEKLRAEHRALVRVVARL 273  Clonorchis sinensis
CDS26837      933 SAS---RpntleyY-------ENQA--------KEIERLRADNARMADENKSLIRVISKL 974  Hymenolepis microstoma
CCD81192      161 RIS---E------C-------EQEL--------KLIDKLRAESEKLHAEHRALIRVVSRL 196  Schistosoma mansoni
XP_002629661  988 KIA---D------L-------ELQL--------KTTQNLRMENQRLKEENGALVRVISKM 1023 Caenorhabditis briggsae
EJW81151      362 RIA---E------M-------QYEI--------EELKKLEKNNDSLRVENEALIRVLSKM 397  Wuchereria bancrofti
XP_003091691 1124 KIA---D------L-------ELQL--------KTTQNLRMENQRLKEENGALVRVISKM 1159 Caenorhabditis remanei
CDJ06265      826 SPAalqR------Rpvd--ffEDQA--------KEIDRLRQENARMADENKSLIRVISKL 869  Echinococcus multilocularis
GAA50590      881 TAQvtdE------LhnrllyhEDQL--------KELNRLREENAKMKEENGALIRVISKL 926  Clonorchis sinensis
CCD59362     1037 SYSnapD------ThniynytSSNNcnnsqipdTEIVRLREEISKMKEENGALIRVISKL 1090 Schistosoma mansoni
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