Conserved Protein Domain Family
RBM39linker
?
pfam15519: RBM39linker (this model, PSSM-Id:292157 is obsolete and has been replaced by 464757)
linker between RRM2 and RRM3 domains in RBM39 protein
A conserved linker between the second and the third RRM domain in human RBM39 (CAPER) protein, also present in other RNA binding proteins, especially those involved in RNA splicing. This linker was implicated in interactions with ESR1 and ESR2. Preliminary results from JCSG suggest that this is a structured domain with a well defined fold.
Links
?
Statistics
?
PSSM-Id: 292157
Aligned: 97 rows
Threshold Bit Score: 68.4798
Created: 20-Jul-2015
Updated: 5-Aug-2015
Structure
?
Aligned Rows:
Download Cn3D
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Q012Z9       215 LDED-G---GGLKMDSRGRAALMARLAGqDKeiEKGFTIDPATGLPTTVD-AIKPidapgedlplaAqpi---------- 279 Ostreococcus tauri
EFX83536     199 SDEM-Dr--AGIDLGATGRLQLMAKLAQ--Gt-GLEIPAAAQSALNL-QA-SIQA-----------Aqqq---------- 249 common water flea
NP_001135965 328 vDEL-Dr--AGYDLGATGRLQLMYKLAE--Gt-GFPIPQAAANALQVASG-VQAA-----------Pa------------ 377 pea aphid
XP_011432153 315 SDEM-Dr--AGIDLGATGRLQLMAKLAE--Gt-GFQIPEYAVSALNITQQ-APGV-----------Asaappagpapnvs 376 Pacific oyster
XP_009025967 342 aDEV-Dk--AGFGMNATSRIQLMAKLAE--Gt-GFEIPKAAASVLNGGGGgVAKL-----------Sptn---------- 394 Helobdella robusta
XP_001992854 458 tDEM-Dr--SGIDLGATGRLQLMFKLAE--Ga-GLAVPQAAANALLATAP-QPAPm------------------------ 506 Drosophila grim...
EGT33870     317 LDDIgDr--QGFSLGAGGRQQLMAKLAQgTGs-GMELTASAQMAAQHAGN------------------------------ 363 Caenorhabditis ...
XP_001626026 303 LDDE-EyekGGVELNSSARAALMAKLSQgHSa-GLSVPGAPPIVSGVQQA-LA--------------------------- 352 starlet sea ane...
XP_011409901 383 gEDM-Dv---GVGMTPQSRVALMHKLAAgHNa-DMSIPGVQVPPPPFAVP------------------------------ 427 Amphimedon quee...
XP_009012913 465 hpkpthstsTGFNLGPTERLQLMAKLAE--Gt-GMQLP--------------AAA-----------Ttai---------- 506 Helobdella robusta

Q012Z9       280 ------tqGVLGPGSPIPTPCLLLKNLFNAAEETDPE 310 Ostreococcus tauri
EFX83536     250 ------alPVASVAPPIATQCFMLSNMFDSSSETHPl 280 common water flea
NP_001135965 378 -------aPTVQVTPPIATQCFLLANMFDPNKEdvds 407 pea aphid
XP_011432153 377 ailgsqaaGQDNTAPPIATQCFMLSNMFDPNAESrss 413 Pacific oyster
XP_009025967 395 ------qkQADAPAPPIATQCFLLSNMFTANELKDAE 425 Helobdella robusta
XP_001992854 507 --------QHEQQTPSIATQCFILSNMFDPRTETNPt 535 Drosophila grimshawi
EGT33870     364 -----------SQIPSIATQCFLLSNMFDPSKETEPN 389 Caenorhabditis brenneri
XP_001626026 353 ----------TPVAVSLPTPCFMLTNMFDPTKERDAG 379 starlet sea anemone
XP_011409901 428 -----------TMPTCITSCCFVIGNMFDPSKETGSD 453 Amphimedon queenslandica
XP_009012913 507 ------saSNQAVTPPIATQCFMLSNMFDLKKQNAAN 537 Helobdella robusta
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap