4A0K,4UI9


Conserved Protein Domain Family
zf-rbx1
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pfam12678: zf-rbx1 (this model, PSSM-Id:289448 is obsolete and has been replaced by 463669)
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RING-H2 zinc finger
There are 8 cysteine/ histidine residues which are proposed to be the conserved residues involved in zinc binding. The protein, of which this domain is the conserved region, participates in diverse functions relevant to chromosome metabolizm and cell cycle control.
Links
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Statistics
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PSSM-Id: 289448
Aligned: 111 rows
Threshold Bit Score: 50.4809
Created: 21-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4A0K_B        30 RFEVKKWNAVALWAWDIVV---DNCAICRNHIM--------DLCIECQANQASAtseeCTVA-WGVCNHAFHFHCISRWL 97  house mouse
A0BNG9        22 rwkaeQLN--------------QNCCSCKKLMT--------EPCIDCEVNDQNDeqekCIAVqSGNCGHALHQHCIRKWI 79  Paramecium tetr...
Q4QEV4        27 YVTARSVPRETLL----MT---GDCPICKSALG--------QPCLKCTSSTDE-----CPVV-VGVCSHIFHQHCLEQWL 85  Leishmania major
Q4D6X3        77 sIPVIMKEALLFFAYEHPVigsLECLVCKLHLE--------ECCLGCRGKGNPVe--eCHVV-RGTCDHTFHDHCIQSWC 145 Trypanosoma cruzi
Q9FI95        68 pqppMCPREIAAMIKDIVVdveLCCPICLEDLK--------------KVDNDDDkvvvCLSK----CNHSFHMNCIFSWL 129 thale cress
XP_001322184  31 mFVVYKFNPVYLSSWQGKQ---DICAICKSSFM--------SPCSTCESKGLSEp---CAAT-EGKCGHKFHKHCIDQWL 95  Trichomonas vag...
XP_001312502  32 eLKITKISAVYQEISSRVT---DNCGICKTPLG--------EPCNNCAIQGATE----CPIE-EGTCGHAFHKHCLSQWL 95  Trichomonas vag...
XP_001565234 304 ppalldscmkplrgssIEA---GTCAICQEELSgtfstataDAAPTATSPSNTDk--aCVKL-L-NCSHAFHKVCINQWL 376 Leishmania braz...
YP_002154623 101 vaQVLRFKAIRVRKLD------EVCVICQEKTS---------------FETS------VRIL---DCGHFFHHACVQEWL 150 Feldmannia spec...
XP_001709040   8 SITIKNWYAVVEWSYNIDE---ANCSICKSPLS--------ELCPECADLLTPV----CRSV-RGRCGHEYHTHCIQQWV 71  Giardia lamblia...

4A0K_B        98 KT------RQVCPLDN 107 house mouse
A0BNG9        80 QTksqggtSGTCPMCD 95  Paramecium tetraurelia
Q4QEV4        86 QG--------TCPLCR 93  Leishmania major
Q4D6X3       146 RQ------RRECPVCF 155 Trypanosoma cruzi
Q9FI95       130 RE------SQDCPICR 139 thale cress
XP_001322184  96 QK------NKHCPMCN 105 Trichomonas vaginalis G3
XP_001312502  96 NT------SRLCPTCg 105 Trichomonas vaginalis G3
XP_001565234 377 TQ------SKTCPICK 386 Leishmania braziliensis MHOM/BR/75/M2904
YP_002154623 151 KR------SPTCPTCR 160 Feldmannia species virus
XP_001709040  72 DS------NKTCPLCM 81  Giardia lamblia ATCC 50803
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