Conserved Protein Domain Family
Ago_hook
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pfam10427: Ago_hook (this model, PSSM-Id:287408 is obsolete and has been replaced by 463088)
Argonaute hook
This region has been called the argonaute hook. It has been shown to bind to the Piwi domain pfam02171 of Argnonaute proteins.
Links
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Statistics
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PSSM-Id: 287408
Aligned: 32 rows
Threshold Bit Score: 36.0846
Created: 28-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8SY33        388 ANPSNPIssvvgpQaRIpsvggvqHKPDGGA-M-WVHSGNv-----gGRNNVAAVTTWGD--DTHSVn--vGAPSSGSVS 456  fruit fly
Q9HCJ0        818 GEPSSPS-----------------TLVDNGT-AaWGKPPSsgs--gwGDHPAEPPVAFGRagAPVAAs--aLCKPASKSM 875  human
Q3UHC0        814 GEPSSPC-----------------TLVDNGT-AaWGKPPSsgs---gwDHPAEPVVPFGRasAPAAAp--aLCKPASKSM 870  house mouse
Q1LZM4         97 SKSTPPA-------------------PDNGT-SaWGEPNEsspgwgeMDDAGASTTGWGN--TPANAp--nAMKPNSKSM 152  house mouse
Q8BKI2        972 SKSTPPA-------------------PDNGT-SaWGEPNEsspgwgeMDDAGASTTGWGN--TPANAp--nAMKPNSKSM 1027 house mouse
Q9UPQ9        938 SKSTPPA-------------------PDNGT-SaWGEPNEsspgwgeMDDTGASTTGWGN--TPANAp--nAMKPNSKSM 993  human
NP_001020014  172 naqvtgallqsesgtapvwskstppaPDNGTsA-WGEPNEsspgwgeMDDTGASTTGWGN--TPANAp--nAMKPNSKSM 246  human
XP_005624105  806 vhskaesswgepsS-PS-------ALVDNGT-AaWGKPPSsgsgwgdQPTEPPVTFGRAS--APTAAp--aLCKPASKSM 872  dog
XP_008766663  806 vhskaenswgepsS-PS-------TLVDNGT-AaWGKPPSsg---sgWDHPAEPVVPFGR--ASAPAaataLCKPASKSM 871  Norway rat
XP_008766664  806 vhskaenswgepsS-PS-------TLVDNGT-AaWGKPPSsg---sgWDHPAEPVVPFGR--ASAPAaataLCKPASKSM 871  Norway rat

Q8SY33        457 SNNW-V-DDKSNSTLAQNSWSDPAPVGVSWGNKQSKPP-SNSASSGWSTAA------GVVDGvDLGSEWnthggIIGK 525  fruit fly
Q9HCJ0        876 QEGW-G-SGGDEMNLSTSQWEDEE-GDV-WNNAASQE--STSSCSSWGNAPkkglqkGMKTSgKQDEAW-----IMSR 942  human
Q3UHC0        871 QEGW-G-SGADEMNLGTSQWEDED-GDM-WNNAASQE--SSSSCSSWGNTSkkglqkGMKTPgKQDEAW-----IMSR 937  house mouse
Q1LZM4        153 QDGWgE-SDGPVTGARHPSWEEEDDGGV-WNTAGSQGStSSHNSASWGQGGkkqmkcSLKGGnN--DSW------MNP 220  house mouse
Q8BKI2       1028 QDGWgE-SDGPVTGARHPSWEEEDDGGV-WNTAGSQGStSSHNSASWGQGGkkqmkcSLKGGnN--DSW------MNP 1095 house mouse
Q9UPQ9        994 QDGWgE-SDGPVTGARHPSWEEEEDGGV-WNTTGSQGSaSSHNSASWGQGGkkqmkcSLKGGnN--DSW------MNP 1061 human
NP_001020014  247 QDGW-GeSDGPVTGARHPSWEEEEDGGV-WNTTGSQGSaSSHNSASWGQGGkkqmkcSLKGGnNdswmnplakqfsnm 322  human
XP_005624105  873 QEGW-G-SGGDDMNLGTSQWEDEE--GGMWNNAAS-QE-STSSCSSWGNAPkkglpkGMKTSgKQDEAW-----IMNR 939  dog
XP_008766663  872 QEGW-G-SGADEMNLGTSQWEDED--GDMWNNAAS-QE-SSSSCSSWGNASkkglqkGMKTPgKQDEAWimsrlikql 943  Norway rat
XP_008766664  872 QEGW-G-SGADEMNLGTSQWEDED--GDMWNNAAS-QE-SSSSCSSWGNASkkglqkGMKTPgKQDEAWimsrlikql 943  Norway rat
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