4LG1,4LEC


Conserved Protein Domain Family
Methyltransf_16
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pfam10294: Methyltransf_16 (this model, PSSM-Id:287289 is obsolete and has been replaced by 313513)
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Lysine methyltransferase
Methyltrans_16 is a lysine methyltransferase. characterized members of this family are protein methyltransferases targetting Lys residues in specific proteins, including calmodulin, VCP, Kin17 and Hsp70 proteins.
Links
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Statistics
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PSSM-Id: 287289
Aligned: 15 rows
Threshold Bit Score: 184.457
Created: 15-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4LG1_A        17 KRDGTVLRLQQYSSG-GVGCVVWDAAIVlskyLETPEFSG-----------DgAHALSRRSVLELGSGTGAVGLMAATL- 83  human
O13926       138 KSPNDGLWFLEQMGN-SIAKHLWDAGVV----FSKKILSDdw-------hyS-FSNRKDINVLELGSGCGIVGISIASKy 204 Schizosaccharom...
Q6CCN8       107 KFDSIPLTIKEDTGN-SIARHVWDAGVT----LAHTLTKEriy-----eqiTgKDSSQQVGILELGAGCGIVGLAVEKHl 176 Yarrowia lipoly...
Q4WP35       142 pKDQLDLRIWEETGN-SIARHIWDAAIAsviyLEQAIAKTpgsaasllgslLqGQGSAPLHVIELGSGCGIVGIALAELv 220 Aspergillus fum...
Q75AY2        31 QLDPP-LKIHEDGGEsGCGGKVWIAGNLlcefILEKSKDGrvl------sqFpGYERQFKNIIELGSGTGLVGLCVGLHg 103 Eremothecium go...
Q8C436        22 KRDGTVLRLQQYGSG-GVGCVVWDAAIVlskyLETPGFSG-----------DgAHALSRRSVLELGSGTGAVGLMAATL- 88  house mouse
Q9CQL0        25 SFANHTIQIRQDWRQlGVAAVVWDAAVVlsmyLEMg-----------------AVELRGCSAVELGAGTGLVGIVAALL- 86  house mouse
XP_001271683 142 PKNQLDLRIWEETGN-SIARHIWDAAIAsviyIQQAISGEpavaapilqdlLqSQRSTPLHALELGSGCGIVGISLAELl 220 Aspergillus cla...
Q5B6H9       137 VNQSVELSIWEETGN-SIARHIWDAAVAsviyLQQMLAGHpgvsnpvlqnaLqTNRSGPLNVIELGSGCGIFGIALAELl 215 Aspergillus nid...
XP_002633495  14 NNDESELTIFQETVT-DVGGVIWDSALMtihyFFKh-----------------PAKFEGKKVLELGSGTGVCGIALAAL- 74  Caenorhabditis ...

4LG1_A        84 ------GADVVVTDLEELQDLLKMNINM--Nk-hL--VTGSVQAKVLKWGEEIEGf---PSPPDFILMADCIYYEESLEP 149 human
O13926       205 -----pRALVSMTDTEDAIEFMEKNVEK--Nk-sA--MSNNITSDILVWGHDIPRk--fRRHWDYIVMSDVMYNESSFSD 272 Schizosaccharom...
Q6CCN8       177 g----gQGSLILSDLEEARECAEESIAL---------NNSSASFMALDWAD---EdvsqLTNLDLIIVADCTYNMDMYET 240 Yarrowia lipoly...
Q4WP35       221 -----pHCSVLLTDLDEVEEIVMKNIAVarP---A--PLSRVRYQPLDWDEKLPGdlcdGH-IDLILVSDCTYNADSLPA 289 Aspergillus fum...
Q75AY2       104 kyngatDTNVYITDIEGLCPLMQKNVELn-------gLDGMVHPRPLFWGEPL-SdeftRQPIDLVLAADCVYLEKAFPL 175 Eremothecium go...
Q8C436        89 ------GADVIVTDLEELQDLLKMNIDMnkH---L--VTGSVQAKVLKWGEDIEDlm-sP---DYILMADCIYYEESLEP 153 house mouse
Q9CQL0        87 ------GAQVTITDRKVALEFLKSNVEA--NlppH--IQPKAVVKELTWGQnLes--fsPGEFDLILGADVIYLEDTFTD 154 house mouse
XP_001271683 221 -----pHCSVTLTDLPEVEEIVTKNIAV--A---HpaPSSHITFQTLDWDEELPEdlcaGH-VDLVLVSDCTYNADSLPA 289 Aspergillus cla...
Q5B6H9       216 -----pQCSVLLTDLPEVEEIITKNIAV--Aq-pA--HASKIQYRPLEWGEELPDdlfgAHTIDLILVSDCTYNADSLPA 285 Aspergillus nid...
XP_002633495  75 ------GADVIITDLPERIPLLEKNLAA--Nk-hL--TGNRIKVEVLDWMTDKTPdg-----lDLVLAVDCVYYNSTITP 138 Caenorhabditis ...

4LG1_A       150 LLKTLKDISGFETC--IICCYEQRtmgknPEIEKKYFELLQLD 190 human
O13926       273 LEASLQELMDKNTK--LYIAYKKR-----HDNEKTFMSNILGW 308 Schizosaccharomyces pombe 972h-
Q6CCN8       241 LVACLERLLKANPSakVVIGHKMR-----NEQESEFFEMLEQR 278 Yarrowia lipolytica
Q4WP35       290 LVDVLDRLVQISPGavVLVALKRR-----HDSEEVFFSLMDSv 327 Aspergillus fumigatus
Q75AY2       176 LEKTLLDLTAGESQplVLMSYKKR-----RKADKKFFIKIKKE 213 Eremothecium gossypii
Q8C436       154 LLKTLKDLSGSETC--IICCYEQRtmgknPEIEKKYFELLQLD 194 house mouse
Q9CQL0       155 LLQTLGHLCSNNSV--ILLACRIR-----YERDSNFLTMLERQ 190 house mouse
XP_001271683 290 LVTVLNRLVQMSPDviVLVALKRR-----HESEEIFFGLMESA 327 Aspergillus clavatus NRRL 1
Q5B6H9       286 LVSVLGRLIELSPHaiVLVALKRR-----HESESVFFDLMESA 323 Aspergillus nidulans
XP_002633495 139 LIDLLKNCDAKE----IIVVSEERdigeaSVAQKTFFKNITEF 177 Caenorhabditis briggsae
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