1KS6


Conserved Protein Domain Family
ecTbetaR2
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pfam08917: ecTbetaR2 (this model, PSSM-Id:286061 is obsolete and has been replaced by 462632)
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Transforming growth factor beta receptor 2 ectodomain
The Transforming growth factor beta receptor 2 ectodomain is a compact fold consisting of nine beta-strands and a single helix stabilized by a network of six intra strand disulphide bonds. The folding topology includes a central five-stranded antiparallel beta-sheet, eight-residues long at its centre, covered by a second layer consisting of two segments of two-stranded antiparallel beta-sheets (beta1-beta4, beta3-beta9).
Links
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Statistics
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PSSM-Id: 286061
Aligned: 17 rows
Threshold Bit Score: 152.473
Created: 16-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1KS6_A         4 RLCKFCDVKATTCSNqDQCTSNCNITSICEKNNEVCAAVWRRNDENVTLETICHDPQKRLYGH---MLDDSSSEQCVMKE 80  chicken
P38438        49 QLCKFCDVTLSTCDNqKSCMSNCSVTSICEKPQEVCVAVWRKNDKNITLETVCHDPKFTYHGF---TLEDATSPTCVMKE 125 Norway rat
XP_012002509  49 QLCKFCDVRSSTCDNqKSCWSNCSITAICEKPEEVCVAVWRKNDENITLETVCHDPKIAYHGF---VLDDAASPKCIMKE 125 mouflon
XP_006635681  50 lLCKFCDFEPSTCDGrSNCFSNCSKTAICEKPQEVCVSIWRKDDNNVTIETLCHDPAEKIYGL---LLDDYNSTKCYMKE 126 spotted gar
XP_007669245  45 gLCKFCDVESTICTNqGVCKSNCSITSICENTFDICAAVWRKNDENITLETICHDQRLPLHGF---DLDDIGSSKCMMKE 121 platypus
XP_004549057  33 KLCKFCDIQPTNCSGkGNCKVECGITSICPQKEDVCVSIWRKKDGNVTFDTVCHNPAEKLYGL---VLKDYNNSECEMKE 109 zebra mbuna
AKA60248      66 NLCRWCEVSTPVCEG-NICSSNCNLTSFCNTTEEICIAIWRKANNTMTVYTMCHHPNLPLDGIspdLLRTFTSRECRMVP 144 Nile tilapia
CAG05723       5 KLCKFCDVRATSCTGiGSCTVGCEITSTCADKEEVCVSIWRKAGSNVTFDTVCHNPAYKLYGL---VLDDYNNSKCEMKE 81  spotted green p...
XP_005993765   5 NLCLFCDLEPTNCEAqGSCKPTCNRTSICEDPQEVCIAIWRKKGTNVTIETVCHDPKKKLHGF---DIEDFESNTCEMKE 81  coelacanth
XP_002941621 207 vLCRFCDVKETTCENqGYCTSVCNIASVCEHQEEVCIAIWRNKDGNITEETMCHDPKKELYGY---KLDDYNEKECIMKE 283 western clawed ...

1KS6_A        81 KKDDGGLMFMCSCTGE-ECNDVLIFSAI 107 chicken
P38438       126 KKRAGETFFMCSCNTE-ECNDYIIFNEE 152 Norway rat
XP_012002509 126 RKGSGETFFMCSCSAE-ECNDHIIFSEE 152 mouflon
XP_006635681 127 KKFPGSLFYVCSCTEE-ECNNKLIFSPE 153 spotted gar
XP_007669245 122 KKMLGETMFMCSCSSE-ECNDLLYFSEE 148 platypus
XP_004549057 110 LSGMGSKFFICSCSED-ECNERVFFDPr 136 zebra mbuna
AKA60248     145 QAANDS-MMVCGCQGEhECNDKLVFDKG 171 Nile tilapia
CAG05723      82 IKGMGSKFFICSCSTD-ECNEHIFFNPt 108 spotted green pufferfish
XP_005993765  82 KKVPDWQVYMCACLGE-ECNGDLIFTKm 108 coelacanth
XP_002941621 284 KKTSEGIMSMCSCRGK-LCTERFYFPPa 310 western clawed frog
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