1OWX


Conserved Protein Domain Family
RRM_3
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pfam08777: RRM_3 (this model, PSSM-Id:285930 is obsolete and has been replaced by 400913)
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RNA binding motif
This domain is found in protein La which functions as an RNA chaperone during RNA polymerase III transcription, and can also stimulate translation initiation. It contains a five stranded beta sheet which forms an atypical RNA recognition motif.
Links
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Statistics
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PSSM-Id: 285930
Aligned: 13 rows
Threshold Bit Score: 92.7855
Created: 16-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1OWX_A         18 GcllkFSGdLDDQTC-REDLHILFSNHG---EIKWIDFVRGAKEGIILFK--EK--AKEALGKAKDA----NngnLQLRN 85   human
Q6K6X2        330 G----LSGkANSPIS-REDLKEAFKKFG---TVRYVDFSIGDESGYLRFEdsKA--AEKARMSAVLAde-gG---LIVKD 395  Japanese rice
Q54TG6        229 GvilcFKG-VGKGLH-RGDIKEIFSQYG---EVQFVGYNSDEENGSVRYKtaES--CKRAIESLTET----K---KEIGG 294  Dictyostelium...
Q7ZTI0        229 GcllkFSGeL-GQTS-REDFHSVFSDHA---QIKWIDFTRGAKEGTILFHs----nAKEALQKVREAlngeD---PKVKE 296  zebrafish
P05455        231 GcllkFSGdLDDQTC-REDLHILFSNHG---EIKWIDFVRGAKEGIILFKe----kAKEALGKAKDAnn-gN---LQLRN 298  human
Q7PWI4        261 GacvfMEG-LGKETT-RESIKEAIRALDetlEFAYIDYQKGDASGYVRFNkqDA--GKQLLEKLTDK----K---LKIDD 329  Anopheles gam...
Q17EQ5        250 GacvhLAG-FNKETS-RETIKETILKLDeslEVAFIDYQKTDSEGTVRFAadDA--GKKFMEKLTDS----K---IQIDE 318  yellow fever ...
Q7ZWE3        429 GvivkIS--YNQPLPsKRCIKDMLSELS---PVAYVDLLDGDTEGHVRFKssED--AQKVIKARFEF----------QKK 491  zebrafish
Q4G0J3        454 GvivkII--STEPLPgRKQVRDTLAAIS---EVLYVDLLEGDTECHARFKtpED--AQAVINAYTEI----------NKK 516  human
CAF96679     1532 GvivkIT--DSKALPaRSRIKDALSRLS---PVAYVDVLEGDAEGHVRFHspED--ARAACEGRAAL----------QKE 1594 spotted green...
CAG09938      211 GcllkFSG-ELEDVS-REDFHELFSGHG---KIKWVDFARGAKEGALLFDg----nAKEAFEKAKEA----NggeLKIKD 277  spotted green...
O01806        230 GlilaVDG-LGPDST-IDSIKTFFKLHG---SVGYVAHENGGKTAEIRFNndSEg-AQKAWDNAVAAgtdgK---VILQE 300  Caenorhabditi...
XP_002638994  232 GlilaVDG-IKGESS-VDSIKTFFKQYG---SVGYVAHEVGNATAEVRFNndSEggAQKAWEKAVEAgtdgK---VMMND 303  Caenorhabditi...

1OWX_A         86 KEVTWEVLEGEVEKEALKKIIEDQQESL--NKWKSKGR 121  human
Q6K6X2        396 HIVTLEPVTGEAEKDYWNTIRGIQGKYK--DNRSYKGR 431  Japanese rice
Q54TG6        295 QIPTYNLLEGEEEKKEWEKIIERKKNAA--KNGGFKKG 330  Dictyostelium discoideum AX4
Q7ZTI0        297 QAVQWEILEGDVEMETLKKIIEDQQESI--NK-RKGGR 331  zebrafish
P05455        299 KEVTWEVLEGEVEKEALKKIIEDQQESL--NKWKSKGR 334  human
Q7PWI4        330 AEVTADLLVDEKETEYLKKIAEEQAKRK--VNAKNKGR 365  Anopheles gambiae str. PEST
Q17EQ5        319 EEITARLLEGDEEKEFLRKVVKDQQARRqaSNARNKGR 356  yellow fever mosquito
Q7ZWE3        492 YNWNLELLSGDHERRYWQKILVDRQAKL--NTPREKKR 527  zebrafish
Q4G0J3        517 HCWKLEILSGDHEQRYWQKILVDRQAKL--NQPREKKR 552  human
CAF96679     1595 LGWRLEVISGEREQRYWQKILVDRQVKL--NRPREKKR 1630 spotted green pufferfish
CAG09938      278 CSVTWQLLEGDEEKEALKRIIEAQQETQ-----RNKGR 310  spotted green pufferfish
O01806        301 AELSARVLDGEEEEKYWTEFNARKNQRQggGRGGRGGR 338  Caenorhabditis elegans
XP_002638994  304 AEITARVLEGEEEEKYWTEFNNRKSQKQ--Nfrggrgg 339  Caenorhabditis briggsae
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