Conserved Protein Domain Family
C8
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pfam08742: C8 (this model, PSSM-Id:285899 is obsolete and has been replaced by 462584)
C8 domain
This domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin. It is often found on proteins containing pfam00094 and pfam01826.
Links
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Statistics
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PSSM-Id: 285899
Aligned: 873 rows
Threshold Bit Score: 31.5342
Created: 21-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P57999        808 QFCGQLVDSrgVFKTCLLHLKASSFFDNCVFDTCNFQ--G---L-QLM--LCAHMSAVTAACQdAGYAVkPWREPQFC 877  rabbit
XP_006004294 1055 NSCNILVSD--IFQECTQLIDPEPYWEICTYDTCACEsiG---D-CAC--FCNAVAAYAQECTqQGIIV-QWRSNNLC 1123 coelacanth
NP_001243217 1056 NACNILMGD--LFAECAKVVNPEPYWEICTYDTCTCEsaG---D-CAC--FCDSLAAYAHVCAqRGINV-HWRSSHLC 1124 western clawed ...
XP_006633894 1036 QTCLILTSE--LFKQCNSVVNPEPYWEICTHDTCSCKsiG---D-CTC--FCDVIAAYAHKCAqRGVVI-HWRSNSLC 1104 spotted gar
XP_003771258 1052 SSCRILTSDt--FRECNKLVDPEPYLDICIYDTCSCEsiG---D-CAC--FCDAIAAYAHVCAqHGTVV-NWRTDTLC 1120 Tasmanian devil
CAG13074     1133 QSCRVILSS--LFKECNSEVDAEPYMDMCVEAACSCS--S---V-DDCacFCDVIAAYAQVCSeKGVTI-SWRSNDLC 1201 spotted green p...
XP_005470844 1046 QSCRILTGS--LFKECNSQVDAEPYVEMCVEAACSCPsvG---D-CQC--FCDVIAAYAQACSeSGVFV-NWRSNDLC 1114 Nile tilapia
NP_001268918 1044 QSCRVLTSA--IFRDCNSVVDPEPYWDICTQDTCSCPsvG---D-CAC--FCNTIAAYAHECAqKGLPV-NWRSNDLC 1112 zebrafish
XP_005012697 1068 TSCSIL--SgsLFEECKKLVDPEPYIDICMYDTCACEstG---D-CAC--FCDAIAAYAHVCAqKGVIV-HWRSADLC 1136 mallard
XP_002593898  702 NRCGKIHq--yPFDQCHSAVEPAEFYESCLYGYC-LW--QdpdSrEQS--LCTSLTAYSRECAqKNVIF-FWRGEGFC 771  Florida lancelet
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