Conserved Protein Domain Family
HNOBA
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pfam07701: HNOBA (this model, PSSM-Id:285003 is obsolete and has been replaced by 462234)
Heme NO binding associated
The HNOBA domain is found associated with the HNOB domain and pfam00211 in soluble cyclases and signalling proteins. The HNOB domain is predicted to function as a heme-dependent sensor for gaseous ligands, and transduce diverse downstream signals, in both bacteria and animals.
Links
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Statistics
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PSSM-Id: 285003
Aligned: 64 rows
Threshold Bit Score: 150.362
Created: 27-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5YLC2       231 FTLSPNDFYQLFPFHLLLDRSCRVVQAGAVLERLFpeLRGRS-GVPLGDVFQMRAP-S-MT-ISFDSLHAAHADtVLLra 306  Chlamydomonas ...
XP_004993125 203 VAMPPSLTNDLFPWHVAFDRDMKIASLGKHLASRL--KRKQI-GAQAWQVFKVVRP-SsMR-LKFDDMLQVQGApILLsv 277  Salpingoeca ro...
XP_004989181 203 idLGKSVTNDLFPWHFAFDRDMKIVSLGKHLAARFe-EP-QA-GKPFKKVFRMLRP-VdIS-SEFDELKDVDGVsCLFsv 277  Salpingoeca ro...
XP_004988344 204 LSADTGLFDELFPWHVQIDRKMRVVSMGSSLQTRFq-DQKLD-SLTFHDVFKLTQP-N-VPqKTFTTFMQFDHDaFVAia 279  Salpingoeca ro...
XP_004989530 203 vdLPASVTNDLFPWHVAFDRDMNIVSVGKHLAGRF--KKQQL-GAKAGSVFKIIRPsH-VR-LKFDELMQAKDVpVLLsv 277  Salpingoeca ro...
XP_004997522 202 cdattteFDELFPWHLQVDSDLRVISMGSSLALRFn-EEELKkQKRLMDVVTVTRPnH-VL-NDFEHLKQFDRTaVMLmv 278  Salpingoeca ro...
XP_001748626 205 VSMDSAAIDRLFPWHFAFDEELKIVSIGSQLRRHLn-A-NPI-GSKLADIMAIQRP-LeAK-YRYDDFQQRSGNpYQLal 279  Monosiga brevi...
XP_004993124 203 vdLPTEVTNELFPWHVAFDRDMKIASVGKHLAARF--KKQQL-GASASHVFKLVRP-LgMS-FSFDSLKTTQGApILLsv 277  Salpingoeca ro...
XP_004997927 203 aqLDATMTNRLFPWHFAVDKDMRIISLGKHLASRM--KKDCV-GMHADKLFRIARP-IdAT-WDFEDMRARCDKpFLFvt 277  Salpingoeca ro...
XP_004997875 203 aQLNAGMTNRLFPWHFAVDKDMKIVSLGKHLASRM--KKDCI-GMHAEKLFRIARP-IdAT-WDFEDIKARCDKpFLFvt 277  Salpingoeca ro...

Q5YLC2       307 r------------------------------------------------------------------------------- 307  Chlamydomonas ...
XP_004993125 278 dakhlthevtvdesvvtlthhlpqlqvtdpsgargse------------------------------------------- 314  Salpingoeca ro...
XP_004989181 278 dakllrdddahglasgmqgmslmgnggdmasd------------------------------------------------ 309  Salpingoeca ro...
XP_004988344 280 rdeqyhmkkeqkhmaklraraaehgw------------------------------------------------------ 305  Salpingoeca ro...
XP_004989530 278 dakhlvqpdssddasvsdnadtsvsslsqqmprlqvtedsrgn------------------------------------- 320  Salpingoeca ro...
XP_004997522 279 rdewysqikeqkldekkkaqlmragssl---------------------------------------------------- 306  Salpingoeca ro...
XP_001748626 280 hrdaqadiqiashyaatddnsdacsvaasels------------------------------------------------ 311  Monosiga brevi...
XP_004993124 278 dakhvrkldqqqpqqphqhvhdassantshagsqrptlgpdql------------------------------------- 320  Salpingoeca ro...
XP_004997927 278 npkrmlsaeeysamlterhqqrqlhllkqtnrahleeaetakevqlpsmvdvskphvrlvvneaaeedrnepdadaqsqt 357  Salpingoeca ro...
XP_004997875 278 npkrmlsaeeyaamlserqqrlaqedreqrhsnliqqferqsidahaqekeaa---------------------ddsarl 336  Salpingoeca ro...

Q5YLC2       308 -----------------------------------------------atGLDLKGQVLPVrvlaspepvtatqcaehvrt 340  Chlamydomonas ...
XP_004993125 315 ----------sstgcpfsgtsssfssntsskrssadmllraarltskvdNIKLHGQITYH-------------------- 364  Salpingoeca ro...
XP_004989181 310 ---------------mrsslvscassfrgsnasssdmlmmanrlyakadNIKLHGQLTYN-------------------- 354  Salpingoeca ro...
XP_004988344 306 ---------------------dddddallqrtvscssvegesfisvatdYLYIKGEMIYI-------------------- 344  Salpingoeca ro...
XP_004989530 321 ----qrrstaamsacpfsspgsainstasskrssmdmmlraarlarkvdNIKLHGQVTFH-------------------- 376  Salpingoeca ro...
XP_004997522 307 -------------------fnvdahantpagsamsaaflndqfisatadFLYLQGEFRYN-------------------- 347  Salpingoeca ro...
XP_001748626 312 ----------------nvgcpfsggrrrsdesaissidrmqalrnmpqrIIQLHGEFVAL-------------------- 355  Monosiga brevi...
XP_004993124 321 -----adrgsavggcpfssmssastsaasskrtsvdmmmraarltnkvdNIKLHGQVTYH-------------------- 375  Salpingoeca ro...
XP_004997927 358 deerslvcpmsrrfdalsapslantsgstsrrssldaleqnsryirkptHIKLHGEIVYD-------------------- 417  Salpingoeca ro...
XP_004997875 337 nvprfsgfsgcpmtgrtpsghtsattsaahslrssmdahdiraralrtnNIKLHGEVVFD-------------------- 396  Salpingoeca ro...

Q5YLC2       341 ehgghqrqlaehvgqrdgrpeqDGEQGFLFLGSPWLAGLAGMRQHGICISDIARHDSTRDFVLLAEQRHAETQLKERLET 420  Chlamydomonas ...
XP_004993125 365 ----------------------EESDLLLFVGVPALHSLEEMEAQGINLTELPLHSHGREFLYGAMYQSASAKNTNEVDK 422  Salpingoeca ro...
XP_004989181 355 ----------------------SDHDVVVFFGTPALRSLEEMEAQRIELSEMPLHSHGREFLYGSMFQSASAKNSNEVDR 412  Salpingoeca ro...
XP_004988344 345 ----------------------SKTDTILFAGVPQFSKPEEMYLRGLSLADIPIHSNGREILFSTAHQAATVSIAAELEQ 402  Salpingoeca ro...
XP_004989530 377 ----------------------EASGVLLFVGVPALYSLEEMETQGISLSEMPLHSHGREVLYGSMFQSASAKNTNEVDK 434  Salpingoeca ro...
XP_004997522 348 ----------------------PRDNTLLFVGVPSAQTPEELYKCGLGLPDIPIHSNGREMLFNNVHQSATVGVAAQLEQ 405  Salpingoeca ro...
XP_001748626 356 ----------------------QEGQ-LFFAGAPLLRDVKQLDAQGITMSDLPVHSHASEILYASMFQAMSAKRANKADK 412  Monosiga brevi...
XP_004993124 376 ----------------------EGSDLLLFVGVPALHSLEEMEAQGINLTELPLHSHGREFLYGAMFQSASAKNTNEVDK 433  Salpingoeca ro...
XP_004997927 418 ----------------------EAKQVLLFVGNPLVQSLEELNKQGIDLADMPIHCHGREVLYSAMCQAVSASNSNQVEA 475  Salpingoeca ro...
XP_004997875 397 ----------------------EEQQVLLFVGNPLVQSTEELDTQGIDLADMPIHCHGREVLYSAMCQAVSASNSNEVEA 454  Salpingoeca ro...

Q5YLC2       421 LTLELKDANSRlgemagwLDEERRRSDGLLYQMLPPEVAS-C 461  Chlamydomonas reinhardtii
XP_004993125 423 RMAELDHSMLE-------VQQKKEQIDALLHSILPPVVASsL 457  Salpingoeca rosetta
XP_004989181 413 RMAELDQSMLE-------IQDKKKQIDGLLHSILPPVVASsL 447  Salpingoeca rosetta
XP_004988344 403 TTSDLSRAQQE-------VTHEKHRVQELLHSILPKQVAQcL 437  Salpingoeca rosetta
XP_004989530 435 RMAELDRSMLE-------VQEKKEQIDTLLHSILPPVVASaL 469  Salpingoeca rosetta
XP_004997522 406 VTQDLEKAKRE-------LGLEKKKVHELLSSILPQTVIQyL 440  Salpingoeca rosetta
XP_001748626 413 ELLMLNNNRDE-------VRRQQEITANLLHSILPPRIADaL 447  Monosiga brevicollis MX1
XP_004993124 434 RMAELDHSMLE-------VQQKKEQIDALLHSILPPVVASsL 468  Salpingoeca rosetta
XP_004997927 476 KLADLDRSMIE-------VQEKKEQIDALLSSILPENVANaL 510  Salpingoeca rosetta
XP_004997875 455 KLADLDRSMAE-------VHSKKEQIDGLLHSILPPVVADsL 489  Salpingoeca rosetta
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