Conserved Protein Domain Family
PBP_sp32
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pfam07222: PBP_sp32 (this model, PSSM-Id:284606 is obsolete and has been replaced by 429354)
Proacrosin binding protein sp32
This family consists of several mammalian specific proacrosin binding protein sp32 sequences. sp32 is a sperm specific protein which is known to bind with with 55- and 53-kDa proacrosins and the 49-kDa acrosin intermediate. The exact function of sp32 is unclear, it is thought however that the binding of sp32 to proacrosin may be involved in packaging the acrosin zymogen into the acrosomal matrix.
Links
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Statistics
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PSSM-Id: 284606
Aligned: 3 rows
Threshold Bit Score: 368.633
Created: 26-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q3V140     1 MMNLAAGFLLMLLEVLLLPGTPLSAEES-PasTPGSPLSSTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYE 79  house mouse
AAI21693  31 TFRCFLQAILMLFIIILFKLSITTCEFStP--LPGSPLNKQEYEKFFSLLISESSAETLCTLRYLHGCGDRTIRRFDAYE 108 western clawed frog
BAG35645   1 MRKPAAGFLPSLLKVLLLPLAPAAAQDStQasTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYE 80  human

Q3V140    80 NHGLVPDGAVCSDLPYASWFESFCQFAQYRCSNHVYYAKRVRCS--QPVSILSPNTLKEVESSAEVPPTSMTTPIVSHAT 157 house mouse
AAI21693 109 NHGVTPVGPICTNLESFSHFDSFCDFAKFRCAHRLFYAKRIPCEdhKVTTIQASDAMPKQEVQSVTSSLPAETPKITENG 188 western clawed frog
BAG35645  81 NHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKRVLCS--QPVSILSPNTLKEIEASAEVSPTTMTSPISPHFT 158 human

Q3V140   158 ATEHQafqpwpERLNNNVEE-----LLQSSLSLggKDQQSSR-RPGQEQ---RKQEQIQEHKLEEAQEQEEQEEEEE--E 226 house mouse
AAI21693 189 SSEKE------ERKLHSAEQkpmkaMYKSDESV--KVKAPHLaKPKEKPllsKLQAYLEAHPTARKKPVKEQNEEEVlkI 260 western clawed frog
BAG35645 159 VTERQtfqpwpERLSNNVEE-----LLQSSLSLggQEQAPE---HKQEQgveHRQEPTQEHkqeegqkqeeqeeeqeeeg 230 human

Q3V140   227 EEAKQEEGQGT-E 238 house mouse
AAI21693 261 PYASQESSEGEdD 273 western clawed frog
BAG35645 231 kqeegqgtkegre 243 human
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