A0F081 15 GPSAFIPTEEIL--EEGs------T-HEVMSDVLLSEgrADHINMVMGLHPTYLACFQRTQDALLQLDGPLPLSWRHYIV 85 zebrafish Q54WU6 138 RTTVFTSESQLP--PLNtdd--elT-RKLFQDVFLQHgrVNHLTRILGWHPQYLEKFLLAYNTIMRDPGPLPLHWRNYIG 212 Dictyostelium d... XP_002082835 4 AVDYYADMGQIS--QDCfaa--tqTgASDFDMDELDD--LDQVTQVIGYHPQFHDHFLATQNFIMKGDGPLPNDYRYYLA 77 Drosophila simu... XP_001688028 4 MVEYYSDMGQIG--QDYgsk--nsP-T--------DSsnLDHVTKVIAYHPRYLDHFLNTQKFVMQCDGPLPYDYRNYIA 70 Anopheles gambi... XP_002059309 4 AVDYYAEMGQIS--QDCs--------STDFDMDDLDEc--DQVTQVIGYHPLYRDHFLRTQNFIMKGDGPLPYAYRYYLA 71 Drosophila virilis XP_001630638 102 GPSSFIPSKELP--SMDtdd--eqT-HSLLVDSFLFNgrVPNVTCIIGVHPQYLDWNARTEYFLMRGEGPLPYDWRHYIA 176 starlet sea ane... XP_004348274 294 APSRFIPTPKLM--PMNeepgaeaS-YQVMVDSFLHDcrVSHFVRALSYHPTYLAAFLHTHHFILRGDGPLPAHWRNYIA 370 Capsaspora owcz... XP_003386260 119 GPSSFMSVKDVAgyHESskpvtheL-QQLYENAFLRDarLSNIVQCLSDHPQYLDLFIQTMDFIMNGDGPLNQDVRCYIA 197 Amphimedon quee... XP_004354715 150 kTTSFINETQLP--PLNsnd--qlT-KRLFQEAFLQSgrVNHIIRLLGWHPQYLERFLASYNKVMRDQGPLPLPWRNYIG 224 Dictyostelium f... XP_001361073 4 AVDYFADMGQIS--QDVst---qnP-TFIYPHTRMYT--YIAVRLVIGYHPHFHDHFLRTQNFIMKGDGPLPNDYRYYLA 75 Drosophila pseu...
A0F081 86 ILAAARHQCSYLVQHHSSAFLLAGGDESWLRGVHCAPPKIQHLQTLNKLLAHRPWIITQEHIQELVCPgaEARWSLAELI 165 zebrafish Q54WU6 213 ILAAARYKCSYIIALQEHEFLMNNGDARWLQGIDHIPAKLKNLLKVIELLAHQPWLLPKLDIEYLVKG--TDAWSIAELV 290 Dictyostelium d... XP_002082835 78 IIAAARHQCPYLVKRYEKEFINQGGDSAWLGGLDFIPAKLRAIYDINKILAHRPWLLRKEHIERLTKG--KNSWSLSEVV 155 Drosophila simu... XP_001688028 71 IMAAARHKCTYLVNLYEEIFLANGGDPNWLNGLEHIPPKLRAISDINKILAHRPWLLNKEHVERLTKG--QNSWSLSEVV 148 Anopheles gambi... XP_002059309 72 IIAAARHQCPYLVKRYEKEFINQGGNSEWLNGLDYIPAKLRAIYDINKILAHRPWLLRKEHIERLTKGr-S-SWSLSEVV 149 Drosophila virilis XP_001630638 177 IMAASRHQCSYLVSIYEREFLRYHGDKQWLKGIQHIPKKLHALLDMNKYLAHQPWLVSTQLIEKLLKG--EDNWSLSELV 254 starlet sea ane... XP_004348274 371 IMAAARCGVKYVVSVQQSTFLVNGGDTTWLKGLEFAPVKLQNLDELNMLLAYQPWRVTAEHIRTLLRG--QDSWSLAELV 448 Capsaspora owcz... XP_003386260 198 ILASSRHRCSYLVTYLEMEFRAKGGNVLWLKGISHIPTKISNLLILNKMLCHQPWYISQTHFQELLVG--PDSWSVAELV 275 Amphimedon quee... XP_004354715 225 ILASARYNCGYLVALLEHEYLHSGGDPKWLQGVDHIPQKLKNLLKIVEMMAHQPWLLPNVDIEYLVKG--QDAWSIAELV 302 Dictyostelium f... XP_001361073 76 IIAAARHQCPYLVKRYEKEFINQGGSSEWLRGLDHIPDKLRAIYDINKILAHRPWLLRKEHIELLTKG--INSWSLSEVV 153 Drosophila pseu...
A0F081 166 QAVVLMTHAHSLASFVWGCGIHPEPEQTEDQTLQ------------------------------PC-------------- 201 zebrafish Q54WU6 291 HAMVLICTFLSLSGFVFCCGISPECGLSESNNLS------------------------------SS-------------- 326 Dictyostelium d... XP_002082835 156 HAMVLLSHFHSLSSFVFSCGLTQKLDGLSSPKLK------------------------------SPpaavgalaptilit 205 Drosophila simu... XP_001688028 149 HAIVLLAHYHSLSSFVFSCGLTQELDGASHKIEN------------------------------NN-------------- 184 Anopheles gambi... XP_002059309 150 HAMVLLSHFHSLSSFVFSCGLTQKLDGLSSPKLKgapvsmppqspplppqqqqqqknvlgeislNS-------------- 215 Drosophila virilis XP_001630638 255 HAIVIMAHIHALSSFVYGCGVVPEIDSENGHTFK------------------------------PP-------------- 290 starlet sea ane... XP_004348274 449 QAIVVLTHFHSVSAIAAGAGLTPEVDLEGGHLFA------------------------------TE-------------- 484 Capsaspora owcz... XP_003386260 276 HAVVIMAFFHALAGFCLGCGLNPEIDTELGHTVS------------------------------DQ-------------- 311 Amphimedon quee... XP_004354715 303 HAMILICTFLSLAGFVFSCGILPEYGLASTTTLD------------------------------ER-------------- 338 Dictyostelium f... XP_001361073 154 HAMVLLSHFHSLSSFVFSCGLTQKLDGLSSPKLK------------------------------SA-------------- 189 Drosophila pseu...
A0F081 202 --Spt---------------------------------------------------dsCCSVRGKARNQQEWSEA----- 223 zebrafish Q54WU6 327 --F-------------------------------------------------------SLNDSDCEIEDTAATEN----- 344 Dictyostelium d... XP_002082835 206 ptSpteaqkgkpvl---------------------------------aeislnnanpdYNSQTAASSNGGAPPDSanaaa 252 Drosophila simu... XP_001688028 185 --Vltqktafn----------------------------------------rlndlynSQHPENLPNGDDANIRP----- 217 Anopheles gambi... XP_002059309 216 --Ssag-------------------------------------------------ggnNTKQDYNNTMDNNNSRS----- 239 Drosophila virilis XP_001630638 291 --Tltet------------------------------------------------nqaSFDSGNATTGSESVRSS----- 315 starlet sea ane... XP_004348274 485 --Se-----------------------------------------------------rAELAEQLNSSQDAVGDA----- 504 Capsaspora owcz... XP_003386260 312 --Seivpshftn-------------------------------------palgvggtgSDSEPSSEAMSPACSPP----- 347 Amphimedon quee... XP_004354715 339 --Ts-----------------------------------------------------fSLNESDCEVEDLTASEN----- 358 Dictyostelium f... XP_001361073 190 --PatlgapatataaaapslppqpqpqpllsktvlgeislntggaggtkpdyntqnaaSNNGSGGAPGDGAGGAAgggga 267 Drosophila pseu...
A0F081 224 ----------------------V-----------------------NEV---------------------KLLMERMMMV 237 zebrafish Q54WU6 345 ----------------------T-----------------------AKV---------------------MELLKNRRSQ 358 Dictyostelium d... XP_002082835 253 dgpdatalngylataqqlpqqhG-----------------------ISV---------------------ETLMERMKVL 288 Drosophila simu... XP_001688028 218 ----------------------E-----------------------VTV---------------------DALMQRMKRL 231 Anopheles gambi... XP_002059309 240 ----------------------TgannnfgqhylataelqpqhqcaISV---------------------EALMERMKVL 276 Drosophila virilis XP_001630638 316 ----------------------T-----------------------MTR---------------------DELMARMREV 329 starlet sea ane... XP_004348274 505 ----------------------Td---------------------sSWT---------------------AAMLQRLNAV 520 Capsaspora owcz... XP_003386260 348 ----------------------N-----------------------EQVskylvehyietskltdtrkldDTIKEKLAAV 382 Amphimedon quee... XP_004354715 359 ----------------------T-----------------------IKV---------------------MELLKKKKEE 372 Dictyostelium f... XP_001361073 268 gaaalng---ylataqqlpqqhG-----------------------ISV---------------------EALMERMKVL 300 Drosophila pseu...
A0F081 238 QQQGEEf---tQEEMVTRF------ERERT------------ESLL----EPAD-----------VQRSV--L--P---- 273 zebrafish Q54WU6 359 QQDDDDdd--qLHDRQQDFhnagddSQSSN------------NNTT----TTTTtttttttttntNTTSN--S--Agggd 416 Dictyostelium d... XP_002082835 289 SQKQDEc---sEAELSSRF------QKVEQ------------QTAE----LAAV-----------TPEAA--VgvP---- 326 Drosophila simu... XP_001688028 232 SEKNDEc---sETELSNRF------KHVEQ------------QAAE----LPPV-----------VREAPadV--P---- 269 Anopheles gambi... XP_002059309 277 SQNQDEc---sEAELSNRF------KSVEL------------QTAE----LAAA-----------SPEVA--ValP---- 314 Drosophila virilis XP_001630638 330 RAEQDTlmeasQEELFQHF------EKLES------------GELAhfkdEAAS-----------TPTES--L--T---- 372 starlet sea ane... XP_004348274 521 AGEADv----tEEENVKNF------EKSET------------EFN------TGH-----------IHHAA--S--A---- 553 Capsaspora owcz... XP_003386260 383 SQEEDEt---eEIDNDRQF------AESVS------------SFGL----EKIH-----------SRSVP--T--P---- 418 Amphimedon quee... XP_004354715 373 QEEDDFedggpEIDRQQEF------HNAGNidadnssssssgSSSL----ATTS-----------SSTYG--G--I---- 423 Dictyostelium f... XP_001361073 301 SQNQDEc---sEAELSSRF------KNVEM------------QTAE----LAAV-----------TPGPA--V--Al--- 337 Drosophila pseu...
A0F081 274 -------------DCVSRFVVDADFTYQDFSPRGAQaPP-TMRAQDYSWEDHGFSLMNRLYGEMAQLLDEKFQVACALTY 339 zebrafish Q54WU6 417 sssstlsqssdrmSDFSRYIGNNTMTHTDFDVSSKL-YN-IFSAQEYSWREHGYELVSRYFPDAAPLLDEEFSFVYTMTY 494 Dictyostelium d... XP_002082835 327 -------------TNLSHYVDDANFIYQDFARRGTEsIN-TFRIQDYSWEDHGYSLVDGLYNDVGIFLDAKFRAAYNLTY 392 Drosophila simu... XP_001688028 270 -------------QQLGRYVDDPGFTYQDFARRGAEnIPqTFRIQDYSWDDHGYSLVNRLYNDVGFYLDDKFRAAYNLTY 336 Anopheles gambi... XP_002059309 315 -------------PIISHYVDDASFTYQDFARRGAEnIN-TFRIQDYSWEDHGYSLVDGLYNDVGTFLDEKFRAAYNLTY 380 Drosophila virilis XP_001630638 373 -------------TDLARYLEDPNFRYQDFASRPQQdIS-TFRIQDCSWEEHGFSLFNRLYPDIGTLLDEKFSSTLGLTY 438 starlet sea ane... XP_004348274 554 -------------SDINRFIRRPDFAHEDFDIKSRE-YS-VFRYQDYSWEDHGFSLVDRFYESCAQLLDQQFSIAKTMTY 618 Capsaspora owcz... XP_003386260 419 -------------VNLLRYITDPSYEHEDFTLASAC----TLRAREYSWEDHGFSFLNSLYPLLSELLDEKFKVASEMTY 481 Amphimedon quee... XP_004354715 424 -------------VDMSRYNCNNQLTHTDFDVSSKD-YT-IFSVQDYSWKEHGYELVSRIFPDAAPLLDEEFSFVYTMTY 488 Dictyostelium f... XP_001361073 338 ------------pPNISHYVDDANFIYQDFARRGAEnVN-TFRIQDYSWEDHGYSLVDGLYNDVGTYLDEKFRSAYNLTY 404 Drosophila pseu...
A0F081 340 HTMAMHSHVDTSTLRKAIWNYIQCIYGIRYDDYDYGEVNQLLERSLKVYVKTVACHPEKTTARMYFSFWRQFRHSEKVHV 419 zebrafish Q54WU6 495 YKFNNNTDIDTLPFRRAVWYYVQRVKGMLHDDYNYQEVNMFLSRSLKNFVKKAVCFPETIKRDDYSKLGYSLKPDEKCHL 574 Dictyostelium d... XP_002082835 393 CTMGGIKNVDTSKFRRAIWNYIQCIYGIRHDDYDYGEVNQLLVRPLKMFIKTACCFPERITTKDYDSVLVELQDSEKVHV 472 Drosophila simu... XP_001688028 337 YTIAGRTNVDTSKFRRAIWNYIQCIYGIRHDDYDYGEVNQLLDRSLKMFIKTACCFPERITKLDYDSVLVELQHSEKVHI 416 Anopheles gambi... XP_002059309 381 FTMGGIKNVDTSKFRRAIWNYIQCIFGIRHDDYDYGEVNQLLVRPLKMFIKTACCFPERITTKDYDSVLVELQDSEKVHV 460 Drosophila virilis XP_001630638 439 FTLGDRTNVDTTVFRMATWNYIHLIFGIYHDDYLYTEVNKLMERSYKRYIKKVACVPEKATQEDYLEFMPELTHSEKVHI 518 starlet sea ane... XP_004348274 619 ATMGGQGGIDTQKLRYAVWYYITRVNGILHDDFNYGTVNELLEREVKLYIKRLACSPAEITQAEYVAASRGLLPSEKIHI 698 Capsaspora owcz... XP_003386260 482 RHVGATKDIDTKPFREATWYYIQSIKGIRHDDYNYGKVNKVLSIEYKTYIRMVACFPEKVSLYDFRECMDGLQFSEKVHV 561 Amphimedon quee... XP_004354715 489 YRFNNSTDIDTLPFRRAVWYYVQRVKGMCHDDYNYQEVNMFLSRNLKYYVKKAVCFPDNISKIDYSKLGYDLKPDEKCHL 568 Dictyostelium f... XP_001361073 405 CTMGGIKNVDTSKFRRAIWNYIQCIYGIRHDDYDYGEVNQLLVRPLKMFIKTACCFPERITTKDYDSVLVELQDSEKVHV 484 Drosophila pseu...
A0F081 420 NLLLMEARMQAALLYALRAITRYM 443 zebrafish Q54WU6 575 SLLAVCSHKQASLLYGLYSVMNYQ 598 Dictyostelium discoideum XP_002082835 473 NLMIMEARNQAELLYALREIMRYM 496 Drosophila simulans XP_001688028 417 NLMILEARNQAELLYALREVMRYM 440 Anopheles gambiae str. PEST XP_002059309 461 NLMIMEARNQAELLYALREIMRYM 484 Drosophila virilis XP_001630638 519 NLLLLEARLQAELLYATRAIMKYM 542 starlet sea anemone XP_004348274 699 AILATEANKQAGLMYALHAVMKYM 722 Capsaspora owczarzaki ATCC 30864 XP_003386260 562 NVLVMEARLQAELIYSLKALMSHM 585 Amphimedon queenslandica XP_004354715 569 ALLAVCSHKQAALLYGLYTVMSYQ 592 Dictyostelium fasciculatum XP_001361073 485 NLMIMEARNQAELLYALREIMRYM 508 Drosophila pseudoobscura pseudoobscura
Jiyao W et al.(2023). "The conserved domain database in 2023.",