2K3R


Conserved Protein Domain Family
Rpr2
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pfam04032: Rpr2 (this model, PSSM-Id:281961 is obsolete and has been replaced by 427665)
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RNAse P Rpr2/Rpp21/SNM1 subunit domain
This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologues. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.
Links
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Statistics
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PSSM-Id: 281961
Aligned: 286 rows
Threshold Bit Score: 36.0777
Created: 24-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2K3R_A        17 RIDILFSLAEr---VF--PY-S-PELAKRYVELALLVQQKAKVKIPRKWKRRYCKKCHAFLVPGINARVRLR-Qk---RM 85  Pyrococcus furi...
Q84VV1        25 RHEHLKNLALwsstGD--TP-I-PSLASLLGRRLAADTESTGITTDPD--LVSCQRCETILKPGFNCNVRIE-Kv---SA 94  thale cress
Q5JJY7        42 RVQHLQRLAAwa-gGE--AR-V-GPLGALLGRRLAANAEAAGIPLAAST--FLCQRCETVLQPGFNCTIRIK-Nn---KR 110 Japanese rice
XP_006605596  41 RFEHLKNLAVw----A--TA-I-PSLGAFYGHQFAAFGEATGIPPDPSL--ITCQRCETILQPGFNSTVRIE-Kn---QS 106 soybean
XP_002303587  41 RLEHLQNLASw--aTE--EA-SiPSLAAFFGRQFASSAEALGVPLDPS-ALFQCQRCGTFLRPGFNCTTQIEkNq---SK 111 black cottonwood
XP_009394593  41 RMQHLQRLATw--aSK--EArV-APLAAFLGERLASKAEASGIPLDPST--LLCERCETILQPGNSCSVRIE-Kv---TN 109 wild Malaysian ...
XP_002529729  46 KLEHLQNLSVw--aSR--EA-SiPSLSAFFGRQFAAAGEALGLLPDHAL--IPCQRCETLLQPGLNCTVRIV-KtlakSR 117 castor bean
XP_009140080  23 RHDHLKNLALw--sTSgdTP-I-PSLATFFGRRLAADGEASDIPHDPDL--FSCQRCETVLQPGFNCNVRIE-Kv---SA 92  field mustard
XP_001524750 137 kslHLYNLTHa-------VP-N-NPLHRQFSLRYETLNCDKLINVPPILEHKICMHCGVLQIPGINQTHRID-Yg---KK 203 Lodderomyces el...
CBK24937      26 QIIYLLHLSEg---LL--KT-N-VPLAQQLLIKAKRVSLVANLPFPARFSTLFCNHCYAPLVSQAANSFKLQ-Sk---KR 94  Blastocystis ho...

2K3R_A        86 PHi--------------------------------------------vVKCLECG 96  Pyrococcus furiosus
Q84VV1        95 NVkkkrnrckksn-------------------------nicfpqnnvvYHCNFCS 124 thale cress
Q5JJY7       111 KAkrrkkln--------------------------------tcqnsisYLCHFCG 133 Japanese rice
XP_006605596 107 KLrhrhkksg------------------------------nitqnkvvYKCHFCl 131 soybean
XP_002303587 112 ARrrhkrfst-------------------------------stknnvvYKCHHCl 135 black cottonwood
XP_009394593 110 KRrrrvnksr------------------------------fprqnnviYTCHFCs 134 wild Malaysian banana
XP_002529729 118 RRhkkpnts---------------------------------mqsnvvYNCHFCs 139 castor bean
XP_009140080  93 NKkkhmrrykkkk------------------------pnmflpqnnvvYYCNLCs 123 field mustard
XP_001524750 204 NKkkkkqknksagevvvekendkevedkdededeegettrknqirrlrYKCLFCK 258 Lodderomyces elongisporus NRRL YB-4239
CBK24937      95 RRagn----------------------------------------qlvRVCECCG 109 Blastocystis hominis
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