2A98_A 43 FNQMEDLLADFEGP---SIMDCKMGSRTYleeelvkarerprprkdmyekmvavDPG----APtpeeh------------ 103 human O45050 156 FIEIEDLLQQFHDPtktAIMDIKIGTRTF-------------------------LES----EVsntkkradlyekmvaid 206 Caenorhabditis ... Q29NC7 236 YIELQDLLAGFKDP---CVMDIKMGCRTF-------------------------LES----EVsnatlrpdlyqkmlavd 283 Drosophila pseu... Q5DHU6 88 YLKMQDLLCNFKSP---SVMDCKIGQRTY-------------------------SESev-iADssenfrkdlylkmists 138 Schistosoma jap... Q16JY0 56 YIQLQDLLTDFYQP---CVMDCKIGVRTY-------------------------LEEelskAKekpklrkdmyekmiqid 107 yellow fever mo... Q963D4 244 YLQLQDLLGDFEHP---CVMDCKVGVRTY-------------------------LESelakAKerpklrkdmyekmvqvd 295 honey bee Q8SXS8 419 YLQLQDLLSDYVQP---CVMDCKVGVRTY-------------------------LEEelskAKekpklrkdmydkmiqid 470 fruit fly Q4S8S8 97 YNMMDNLLTHFSTP---AVMDCKMGSRTY-------------------------LEHelqiARerpqprkdmfekmvavd 148 spotted green p... XP_001638916 79 YIEMQDLLQDFDTPc--CVMDCKMGIRTY-------------------------LEDeiakAKskprkdlyqkmvdv--d 129 starlet sea ane... XP_010846292 73 YLQLQDLLDGFDGP---CVLDCKMGVRTY-------------------------LEEeltkARerpklrkdmykkmlavd 124 Bison bison bison
2A98_A 104 ---------aqgaVTKPRYMQWRetMSSTSTLGFRIEGIKkADGTCNTNFKKTQALEQVTKVLEDFV-DGDHVILQkyVA 173 human O45050 207 ndepteeerkcgaITKLRYMQFRerESSTAQLGFRIEAAKrLEGALEKNFKKVRTVEDVTTTFMDFFgTQRSRVRQqlIE 286 Caenorhabditis ... Q29NC7 284 asaptaaehearaiTKLRYMLFResLSSSHTKGFRIEALRlRGRPPVKDLKTCRSSEQISQTIEQFLa-ARKSVQKelLK 362 Drosophila pseu... Q5DHU6 139 pnvpterehrekgVSKLRYLQWRdtISSTAEFGFRIEAIKlPSESTRRDFQHTRKWDEIINHCKLFIq-GRKIIAQnyLL 217 Schistosoma jap... Q16JY0 108 pnapteeehrakgVTKPRYMVWRetISSTSTLGFRIEGIKkSDGTSSKDFKTTKSREQIIEAFREFTe-GFPHALPkyIQ 186 yellow fever mo... Q963D4 296 ptapnaeerrvqgVTKPRYMVWRetISSTATLGFRVEGIKlAHGGSSKDFKTTRTREQVTEALRRFVe-GYPHAVPkyIQ 374 honey bee Q8SXS8 471 shaptaeehaakaVTKPRYMVWRetISSTATLGFRIEGIKkSDGTSSKDFKTTKSREQIKLAFLEFLs-GHPHILPryIQ 549 fruit fly Q4S8S8 149 peaptaqeraqqaVLKTRYMQWRetLSSTASLGFRIEGFRkAKEECHTNFKRTKSRDQVMEALDTFVe-SKSHIMWgyLI 227 spotted green p... XP_001638916 130 pnepteeernegaITKPRYMQWRerLSSSASLGFRIEGIKkGNEKPNKDFKKTKTTDDVYSVFTDYIe-NDDQLRSkyLR 208 starlet sea ane... XP_010846292 125 peapteeehaqraVTKPRYMQWRegISSSTTLGFRIEGIKkADGSCSTDFKTTRSREQVIRVFEEFVq-GDAEVLRryLN 203 Bison bison bison
2A98_A 174 CLEELREALEISPFfkthEVVGSSLLFVHDHTGLAKVWMIDFGK-TVAlpdhqtl--shrlpwaEGNREDGYLWGLDNMI 250 human O45050 287 RLKSMRKAIEHSSFfnshEVVGSSILIVFDTE-KVGCWMIDFAK-SSPvpngrtl--nhrttwiPGNNEDGYLIGIDNLV 362 Caenorhabditis ... Q29NC7 363 RLKHMRLVVEQSAFfnrhEIVGSSIFIVYDDE-RVGAWLIDFAK-CRQlpahmsv--nhrsawtSGNREEGLLKGMDELI 438 Drosophila pseu... Q5DHU6 218 RLLKLRTILEVSDFfakhEFIGSSLLFVHDESGYANIWLIDFAKvTSPspldhkirvnhrskwqCGNYEDGYLIGIDNLV 297 Schistosoma jap... Q16JY0 187 RLKAIRATLSYSDFfkrhEVIGSSLLFVHDRH-NASVWLIDFAK-TVTlpdkvdi--thenkwkVGNHEDGYLIGINNLI 262 yellow fever mo... Q963D4 375 RLKAIRATLKASPFfashEVVGSSLLFVHDTK-NAGIWMIDFAK-TLPlpqhlpri-hhdaewkVGNHEDGYLIGVNNLI 451 honey bee Q8SXS8 550 RLRAIRATLAVSEFfqthEVIGSSLLFVHDQT-HASIWLIDFAK-TVElppqlri--dhysawkVGNHEDGYLIGINNLI 625 fruit fly Q4S8S8 228 RLKQLRQALETSEFfrrhEVVGSSLLFVHDWSGRTGVWMIDFGK-TAPlppelsv--dhrtpwvEGNREDGYLWGLDNLI 304 spotted green p... XP_001638916 209 RLKAIRATLEASAFfsshEVIGSSLLFVHDSSGHASVWMIDFGK-TVPvadgrvl--dhrtpwqEGNHEDGYLWGLDKMI 285 starlet sea ane... XP_010846292 204 RLQHIRDTLEVSEFfrrhEVIGSSLLFVHDHCHRAGVWLIDFGK-TTPlpdgqtl--dhrrpweEGNREDGYLLGLDNLI 280 Bison bison bison
2A98_A 251 CLLQ 254 human O45050 363 KILE 366 Caenorhabditis elegans Q29NC7 439 HAFE 442 Drosophila pseudoobscura Q5DHU6 298 KLFE 301 Schistosoma japonicum Q16JY0 263 DIFQ 266 yellow fever mosquito Q963D4 452 DIFQ 455 honey bee Q8SXS8 626 DIFV 629 fruit fly Q4S8S8 305 DTLS 308 spotted green pufferfish XP_001638916 286 DIWS 289 starlet sea anemone XP_010846292 281 GILA 284 Bison bison bison
Jiyao W et al.(2023). "The conserved domain database in 2023.",