pfam00702: Hydrolase (this model, PSSM-Id:279092 is obsolete and has been replaced by 459910)
haloacid dehalogenase-like hydrolase
This family is structurally different from the alpha/beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure of the family consists of two domains. One is an inserted four helix bundle, which is the least well conserved region of the alignment. The rest of the fold is composed of the core alpha/beta domain. Those members with the characteristic DxD triad at the N-terminus are probably phosphatidylglycerolphosphate (PGP) phosphatases involved in cardiolipin biosynthesis in the mitochondria.
Jiyao W et al.(2023). "The conserved domain database in 2023.",