4M6R


Conserved Protein Domain Family
salvage_mtnB

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TIGR03328: salvage_mtnB 
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methylthioribulose-1-phosphate dehydratase
Members of this family are the methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway. This pathway allows methylthioadenosine, left over from polyamine biosynthesis, to be recycled to methionine. [Amino acid biosynthesis, Aspartate family]
Statistics
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PSSM-Id: 274521
Aligned: 20 rows
Threshold Bit Score: 251.031
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4M6R_A        10 IPELCKQFYHLGWVTGTGGGISL--K--------H--GDEIYIAPSGVQKERIQPEDMFVCDIN-EKDIS--Gpsp--sk 72  human
AAH08440      28 IPELCKQFYHLGWVTGTGGGISL--K--------H--GDEIYIAPSGVQKERIQPEDMFVCDIN-EKDIS--Gpsp--sk 90  human
NP_509690     33 FTELMIQFYKLGWMRGSGGAMGC--I--------S--GSELMISPSALQKERIREQDVFVYNMKdKTEVQ--Rp-----p 93  Caenorhabditis ...
WP_011363497   1 MTEVMRGFHRRGWCDGTGGNFSV--Vl-------QhqPLELLMAPSGVDKGQVPADQLIVVDGQ-GKVLT--G------- 61  Synechococcus s...
WP_012675373  17 LNDIKVKLYNRGWFPATSGNLSY--Klh-----dD--PLYFAITSSGKDKGTVTHEDVIFVDKD-AKPIEk-T------- 78  Persephonella m...
WP_011244413  11 LSWVIQDLHKRGWATGTGGNFSLvtRr-------D--PLRLLMAPSGVDKGLVQPDELIEVDAK-SQVVT--G------- 71  Synechococcus e...
NP_200196     28 VTELCRHFYTQGWVSGTGGSITM--KvhdasipkP--EQLIVMSPSGVQKERMQPEDMYILSAN-GSIIS--Tpspkpyp 100 thale cress
CCU57918      11 LAEVKRELAERDWFPATSGNLSI--Kvt-----dE--PLTFLVTASGKDKRKETVEDFLLVDQN-GEPAE--S------- 71  Bacillus subtil...
WP_011360606  11 LAKTIGDLHGRRWCEGTGGNFSV--Vvq-----hD--PIHLLMAPSGVNKGRLEPAELVIVDEQ-NNVIE--G------- 71  Synechococcus s...
WP_012536138   9 LAAAARDFYARGWMLGTAGNLSA--Rs-------D--TDTFWITASGRPKDRLAAGDFVLVDRQ-GQVVQapP------- 69  Acidithiobacill...
4M6R_A        73 K--LKK--SQCTPLFMNAYTMR-GAGAVIHTHSKAAVMATLLFPGRE-FKITHQEMIKGIKkctsgGyYRYDDMLVVPII 146 human
AAH08440      91 K--LKK--SQCTPLFMNAYTMR-GAGAVIHTHSKAAVMATLLFPGRE-FKITHQEMIKGIKkctsgGyYRYDDMLVVPII 164 human
NP_509690     94 N--KRItvSSCSVLFSLIMKET-GSECVIHTHSKCANLITQLIKSNv-FEISHQEYIKGIYdpfsgKaLKYSDTLTIPII 169 Caenorhabditis ...
WP_011363497  62 K--GKA--SAETELHLRIVEAT-QAGAVLHTHSVPGTVLSRHYETTGgIALEGWEMLKGLV-----GiNTHACCITIPVI 131 Synechococcus s...
WP_012675373  79 K--LKP--SAETKVHSQIYQRT-DAGCVIHIHTVNNNFISQLYFEDGyVPIKDMEMIKAL------DiWKEDAFIKVPII 147 Persephonella m...
WP_011244413  72 N--GKA--SAETLLHLAIIQQT-GAASVLHTHSPIATLLSRRAEVTGaIAFSGYEMQKGLE-----GiTTHETEVHLPVF 141 Synechococcus e...
NP_200196    101 N--KPPkcTDCAPLFMKAYEMR-NAGAVIHSHGMESCLVTMLNPQAKeFRITHMEMIKGIQ-----G-HGYYDELVVPII 171 thale cress
CCU57918      72 GhsLKP--SAETLLHTHLYNKT-NAGCCLHVHTVNNNVISELYGDQKkITFKGQEIIKAL------GlWEENAEVTVPII 142 Bacillus subtil...
WP_011360606  72 R--GRA--SAETTLHLEIIRQL-KCGAVLHTHSIETTVLSAHYARVGtIQLEGWEMLKGLK-----GiTSHETTIDIPIM 141 Synechococcus s...
WP_012536138  70 G--RQP--SAEAAIHETIYRHVpDARVIFHVHSIEAN-LCGHFARQGrLRLPPLEMLKGL------GvPDAEPQVDLPVF 138 Acidithiobacill...
4M6R_A       147 ENTPEEKDLKDRMAHAMN-EYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKV 209 human
AAH08440     165 ENTPEEKDLKDRMAHAVN-EYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKV 227 human
NP_509690    170 DNMPSESQLLEPIRGVLE-NYPQAIAVLVRNHGLFVWGPTWESTKIMTECIDYLLELSIEMLKN 232 Caenorhabditis elegans
WP_011363497 132 SNSQSMDELCDAIAPFLE-TAP--CGFLVAGHGLYAWGADLDASKRHLEILEFLLKVNLNQMQI 192 Synechococcus sp. CC9605
WP_012675373 148 ENFFDLDRLAEEAGKSIN---PEVPGLLIRNHGIYAWGRDEFEAKRHVEAFEFIFEYMRNMIIF 208 Persephonella marina
WP_011244413 142 PNDQDMAALSQAVLPQLQ-AAP-PWGVLIAGHGLYAWGNSLFAARRHVEILEFLLELHYRELTL 203 Synechococcus elongatus
NP_200196    172 ENTAYENELTDSLTKAIE-AYPKATAVLVRNHGVYIWGDSWIHAKTQAECYHYLFDAAIKLHQL 234 thale cress
CCU57918     143 ENPAHIPTLAALFAEEI---SEDSGAVLIRNHGITAWGKTAFEAKRVLEAYEFLFSYHLKLKTL 203 Bacillus subtilis E1
WP_011360606 142 SNNQNIEELSQTVRPYL---SKTIPGILVAGHGLYAWGDSLAEAQRHVEILEFLFSVllkkkll 202 Synechococcus sp. CC9902
WP_012536138 139 ANHLNVARIAEDMDREFTgALPRVPGALIHLHGVTAWGPDFLAARHHLELLEYCFRYLVQAKIL 202 Acidithiobacillus ferrooxidans
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