4B2T,3P9D


Conserved Protein Domain Family
chap_CCT_theta

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TIGR02346: chap_CCT_theta 
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T-complex protein 1, theta subunit
Members of this family, all eukaryotic, are part of the group II chaperonin complex called CCT (chaperonin containing TCP-1) or TRiC. The archaeal equivalent group II chaperonin is often called the thermosome. Both are somewhat related to the group I chaperonin of bacterial, GroEL/GroES. This family consists exclusively of the CCT alpha chain (part of a paralogous family) from animals, plants, fungi, and other eukaryotes.
Statistics
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PSSM-Id: 274087
Aligned: 9 rows
Threshold Bit Score: 843.611
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4B2T_Q        10 GFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMA 89  cattle
P47079         9 PNAGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLGKIIITNDAATMLRELDIVHPAVKVLVMA 88  Saccharomyces c...
P78921         9 SGPQLFREGYRIMQGVEDAVIRNCNAIRELSEITRTSLGPNGKNKIVVNHLQQTFLTNDAATIIRELEVIHPAAKLVVDA 88  Schizosaccharom...
AAQ56831      10 GIQSMLKEGYRHLSGLDEAVIKNIEACKELSTITRTSLGPNGMNKMVINHLDKLFVTNDAATIVNELEIQHPAAKLLVLA 89  thale cress
P50990        10 GFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMA 89  human
AAD34470       8 GINSLLKEGHRHFSGMEEALLKNINACKEISNMTKTSLGPNGMKKMVINHLDKIFVTSDAATIMQEMEVQHPAAKMIVMA 87  Tetrahymena pyr...
XP_001349645   7 gVNSILKDGYRIMKNNEDTILKNIEACKEICNILQTSLGPKCMNKLIINHIHKKIVSSDCITILNDMEINHPVVNILKKL 86  Plasmodium falc...
AAP34647       8 GIPNLFKSGTAHIRGTQEAVMKNIEACKDLATITRTSYGPNGMNKMIINYLEKLFVTSDAATMMAEMEVQHPAAKLLVLA 87  Bigelowiella na...
3P9D_H         9 PNAGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLGKIIITNDAATMLRELDIVHPAVKVLVMA 88  Saccharomyces c...
4B2T_Q        90 SHMQEQEVGDGTNFVLVFAGALLELAEELLRLGLSVSEVIEGYEIACKKAHEILPDLVCC--SAKNLRDVDEVSSLLHTS 167 cattle
P47079        89 TEQQKIDMGDGTNLVMILAGELLNVSEKLISMGLSAVEIIQGYNMARKFTLKELDEMVVG--EITDKNDKNELLKMIKPV 166 Saccharomyces c...
P78921        89 TQQQENELGDAANFVVVFTGELLAKAENMIRMGLTPLEIAKGYEMALSHTMEVLEEICAD--KIETVESEKELIKAIRTC 166 Schizosaccharom...
AAQ56831      90 AKAQQEEIGDGANLTISFAGELLQNAEELIRMGLHPSEIISGYTKAVSKAVEILEQLVETgsETMDVRNKDEVISRMRAA 169 thale cress
P50990        90 SHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCs--AKNLRDIDEVSSLLRTS 167 human
AAD34470      88 SKMQENECGDATNLVIALAGELLSQAESLIKMGLHPSQIITGYEQALKAAIELLNTLSVF--TVEDPTNLEQVSKALKAS 165 Tetrahymena pyr...
XP_001349645  87 SETINYEYGDFTNYAFTITCEILDKASFLIQQGFNINDILNGFVLGYKEIEKVLEEMIVW--KVPNFYEEKELIKVLKSV 164 Plasmodium falc...
AAP34647      88 ARMQEREIGDGSNYVLVLAGELLKQARGLLELGLHPSEIIKGYVQAADVAMASLDELVTWkvEAKELAKKETIETATFAS 167 Bigelowiella na...
3P9D_H        89 TEQQKIDMGDGTNLVMILAGELLNVSEKLISMGLSAVEIIQGYNMARKFTLKELDEMVVG--EITDKNDKNELLKMIKPV 166 Saccharomyces c...
4B2T_Q       168 VMSKQYGN-EVFLAKLIAQACVSIFP-DSGH-----FNVDNIRVCKILGSGVHSSSVLHGMVFKKETEGDVT---S---V 234 cattle
P47079       167 ISSKKYGS-EDILSELVSEAVSHVLPvAQQAgeipyFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVKslsE---D 242 Saccharomyces c...
P78921       167 ISSKQYGN-EDFLSDLVAKAILTVLPkDPSK-----FNVDNIRVVKIMGSSLYNSQVVKGMVFPREPEGTVT---R---S 234 Schizosaccharom...
AAQ56831     170 VASKQFGQ-EEIICSLVTDACIQVCPkNPTN-----FNVDNVRVSKLLGGGLHNSCIVRGMVLKSDAVGSIK---R---M 237 thale cress
P50990       168 IMSKQYGN-EVFLAKLIAQACVSIFPd-SGH-----FNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVT---S---V 234 human
AAD34470     166 LSSKLIHH-ADFFAQIVAQACINSKPeNDDT-----FDLEFVRVAKILGASIEDSYVQQGLIITRNAEGSIT---R---V 233 Tetrahymena pyr...
XP_001349645 165 MLTKNISNnYNFLIQLLAKCISTLMPeKIED-----FDVDNIRVSKLNGGNIIDSEFLMGMVIAREANGIIK---K---K 233 Plasmodium falc...
AAP34647     168 LCSKQLTT-VDILNPLIADACMCVMPkNVKN-----FNVDNVRTCKMMGGSVQHSEVICGVVVNRDTDTSVK---S---V 235 Bigelowiella na...
3P9D_H       167 ISSKKYGS-EDILSELVSEAVSHVLPvAQQAgeipyFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVK---SlseD 242 Saccharomyces c...
4B2T_Q       235 KDAKIAVYSCPFDGMITETKGTVLIKSAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGRVADMALHYANKYNIMLVR 314 cattle
P47079       243 KKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIADMGVECIVAGAGVGELALHYLNRYGILVLK 322 Saccharomyces c...
P78921       235 KEAKVAVFSCPLDISQTETKGTVLLHNAQEMLDFSKGEENLIESHIKEIYDAGVRVVVTSGNVNDLVLHYLNRFEILVIR 314 Schizosaccharom...
AAQ56831     238 EKAKVAVFAGGVDTTATETKGTVLIHSAEQLENYAKTEEAKVEELIKAVAESGAKVIVSGGSIGEMALHFCERYKIMVLK 317 thale cress
P50990       235 KDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVR 314 human
AAD34470     234 SNPKVAVYSCPLDTQQAETKGTVLIQNAKELLNYTKSEESHAESIVKKIADSGINLIIAGGSISEIVLHYVEKYKMMIVK 313 Tetrahymena pyr...
XP_001349645 234 ENANVIVLNCGLEGPTTETKGTVLLHNAEELINYTKGEELQMKKYIDNFKKANVDVIIVNGAISDIAQHFCDTNNIMTLK 313 Plasmodium falc...
AAP34647     236 LDAKVAVFTCAIDTATTETKGTVLIKDADELLDYNKSEERMIEASIKAIADSGVKVIVTGGSVGDMAKHFVEKYGMMLIR 315 Bigelowiella na...
3P9D_H       243 KKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIADMGVECIVAGAGVGELALHYLNRYGILVLK 322 Saccharomyces c...
4B2T_Q       315 LNSKWDLRRLCKTVGATALPRLNPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKED-GAISTIVLRGSTDNLMDDIERAVD 393 cattle
P47079       323 VPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVTVFKQEQGEiSRTSTIILRGATQNNLDDIERAID 402 Saccharomyces c...
P78921       315 VPSKFELRRLCRVVGATPLARMGVPMPEEMGSVDVVETIEIGGDRVTVFRQVEDi-TRTATIVLRGATKTYLDDLERAID 393 Schizosaccharom...
AAQ56831     318 ISSKFELRRFCRTAGAVAHLKLSRPSPEDLGYVDSISVEEIGGVTVTIARNEEGG-NSISTVVLRGSTDSILDDLERAVD 396 thale cress
P50990       315 LNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKED-GAISTIVLRGSTDNLMDDIERAVD 393 human
AAD34470     314 CQSKFELKRICKALGACPVARLDAPNPEEIGFCDSASVEEIGSQKVTIIKKENQD-CKLNTIILRGSTINFLDDIERAID 392 Tetrahymena pyr...
XP_001349645 314 ITSKFETLRICKLLNISSLIKLSTPQPEDIGKVSSIYVSEIASKKVTIINSKNK---KVGTIILRGATFNLLDEVERCIH 390 Plasmodium falc...
AAP34647     316 ILSKFELRRLAKTVKANMQVRLGAVPPEAQGYCAKAYVREVGLQKVTVFEQKKTDlSQIATIMLRGSTKNILNDIERAVD 395 Bigelowiella na...
3P9D_H       323 VPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVTVFKQEQGEiSRTSTIILRGATQNNLDDIERAID 402 Saccharomyces c...
4B2T_Q       394 DGVNTFKVLTRD--K--RLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYA 469 cattle
P47079       403 DGVAAVKGLMKP--SggKLLPGAGATEIELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYA 480 Saccharomyces c...
P78921       394 DGVNIVKALVKD--N--RLIFGAGASDMQLCIRLISVGEKTPGIYQHAIKQYGEAFEVVPRTISENAGLDPTDVISKLYA 469 Schizosaccharom...
AAQ56831     397 DGVNTYKAMCRD--S--RIVPGAAATEIELAQRLKEYANAEIGLDKYAITKYAESFEFVPKTLADNAGLNAMEIIAALYT 472 thale cress
P50990       394 DGVNTFKVLTRD--K--RLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYA 469 human
AAD34470     393 DGVNVYRCLLKD--G--KFAAGAGATEAVLSHKLQQQAKSLEDLSQYAFNRFALSFEIIPRILSDNAGLNSNEIIPKLNT 468 Tetrahymena pyr...
XP_001349645 391 DGINSIKNAIKG--N--AFLHGGGCVEIQLCLALKKYANQLKGVDNYCVKIFAEAFYIIPKILARNAGYNTTDVLNELIN 466 Plasmodium falc...
AAP34647     396 DGVNVIKSLVKD--G--RFLPGGGATEIELARKLAELSNKEKTLSQYAIKKFAQSFEIIPTTLAENAGLKPLDVLTLLYS 471 Bigelowiella na...
3P9D_H       403 DGVAAVKGLMKPsgG--KLLPGAGATEIELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYA 480 Saccharomyces c...
4B2T_Q       470 VH--------QEGNKNVGLDIEAEVP--AVKDMLEAGVLDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGK 539 cattle
P47079       481 AHnvtepgavKTDHLYKGVDIDGESDe-GVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAKKAGGPRAPQGP 559 Saccharomyces c...
P78921       470 AHh-------KENGESIGVDVECEND--GTLDAKEAGIFDVLLAKKSAIRLATETVLTVLNVDQVVMSKPAGGP-KPPGP 539 Schizosaccharom...
AAQ56831     473 GH--------GSGNTKLGIDLEEGAC----KDVSETKVWDLFATKLFALKYASDAACTVLRVDQIIMAKPAGGPRRDAAQ 540 thale cress
P50990       470 VH--------QEGNKNVGLDIEAEVP--AVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGK 539 human
AAD34470     469 AN---------K-EESYGIDIENGTIr----KSSELAVYDHLQSKIWAVRLAADAAITILKVDQIVIAKQAGGPKMNQQQ 534 Tetrahymena pyr...
XP_001349645 467 EH--------NKGNTHSCININKDSH---ITSAQNNHIYDNYNCKKYAIHLAMEAVQTILKIDQIIMSKPAGGPKPRDKN 535 Plasmodium falc...
AAP34647     472 EH--------ESGKKSAGINIDAQDVkqSVKDLAKDRIFDSLPAKKMAIKLATDAAVTVLRVDQIIMAKPAGGPKMGQRK 543 Bigelowiella na...
3P9D_H       481 AHnvtepgavKTDHLYKGVDIDGESDe-GVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAKKAGGPRAPQGP 559 Saccharomyces c...
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