2I0Q


Conserved Protein Domain Family
TEBP_beta
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pfam07404: TEBP_beta (this model, PSSM-Id:254188 is obsolete and has been replaced by 462156)
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Telomere-binding protein beta subunit (TEBP beta)
This family consists of several telomere-binding protein beta subunits which appear to be specific to the family Oxytrichidae. Telomeres are specialized protein-DNA complexes that compose the ends of eukaryotic chromosomes. Telomeres protect chromosome termini from degradation and recombination and act together with telomerase to ensure complete genome replication. TEBP beta forms a complex with TEBP alpha and this complex is able to recognize and bind ssDNA to form a sequence-specific, telomeric nucleoprotein complex that caps the very 3' ends of chromosomes.
Links
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Statistics
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PSSM-Id: 254188
Aligned: 4 rows
Threshold Bit Score: 609.421
Created: 20-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I0Q_B     1 MSKGAsApQQQSAFKQLYTELFNNEGDFSKVSSNLKKPLKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNI 80  Sterkiella nova
EJY73188   1 MSKSQqV-QQQSAFKQLYTELFNNGGDFGKVSNNLKKPLKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNI 79  Oxytricha trifallax
P16458     1 MSKGAsApQQQSAFKQLYTELFNNEGDFSKVSSNLKKPLKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNI 80  Sterkiella nova
P29548     1 MSKGQ-A-QQQSAFKQLFTEFFNLGGDFSKVSKDLKKPLKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNI 78  Stylonychia mytilus

2I0Q_B    81 VDLTDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTRYPVNLFRDDEFKTTIQHFRHTALQAAI 160 Sterkiella nova
EJY73188  80 VDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTRYPVNLYRDDEFKTTIQHFRHQALQQSL 159 Oxytricha trifallax
P16458    81 VDLTDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTRYPVNLFRDDEFKTTIQHFRHTALQAAI 160 Sterkiella nova
P29548    79 VDLHDKVIVINSWSLELRRVNSAEVFTSYANLEARLVVHSFKPNLQERLNPTRYPVNLFRDDEFKTIIQHFRHQALQQSI 158 Stylonychia mytilus

2I0Q_B   161 NKTVKGDNLVDISKV--ADaagKKGKVDAGIVKASASKGDEFSDFSFKEGNTATLKIADIFVQEKGKDALNKAADhTDGa 238 Sterkiella nova
EJY73188 160 AKNLKQENIPDIAKVtgGD---KKAKVDAGIVRASTSKGDEFSDFSFKEGNTATIRIQDIFVQEKGKDALSKLGGeGDV- 235 Oxytricha trifallax
P16458   161 NKTVKGDNLVDISKV--ADaagKKGKVDAGIVKASASKGDEFSDFSFKEGNTATLKIADIFVQEKGKDALNKAADhTDGa 238 Sterkiella nova
P29548   159 AKNTKQESLPDISKLsgADaagKKTKVDGGIVKTGASKGDEFADFSFKEGSTAVLKIQDIFVQEKGKDALKRIQD-QQVe 237 Stylonychia mytilus

2I0Q_B   239 ------KVKGGAKGKGKAAAKAAk-GKKLSAKKGdS-SAADVRKSVDKIVKYTPSK-GSRKDTPQKSQa----PAAGKSS 305 Sterkiella nova
EJY73188 236 ------KVKGGARGKAKAASKSAarGKKGSAKKAdVgASADVRKSVDKIVKYTPNKpSSRKETPQKSQsv-paGKSSAKK 308 Oxytricha trifallax
P16458   239 ------KVKGGAKGKGKAAAKAAk-GKKLSAKKGdS-SAADVRKSVDKIVKYTPSK-GSRKDTPQKSQap-aaGKSSAKK 308 Sterkiella nova
P29548   238 svqvqpKVRGGAKGKKKAATKSA--TKKTVAAKK-TaESADVRKSVDKIVKYTPNKpSSRKETPQKSQsapaaGKSSAKR 314 Stylonychia mytilus

2I0Q_B   306 AKKGGKKAVPSAPSPSGKKSALTTDKMTMAQFVKYLDWHEKKKGGKVSSGGKVLGKRSAGKASATSG 372 Sterkiella nova
EJY73188 309 TTTGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKNVGKTSSGGKVLGKRSAGKASATSG 375 Oxytricha trifallax
P16458   309 ---GGKKAVPSAPSPSGKKSALTTDKMTMAQFVKYLDWHEKKKGGKVSSGGKVLGKRSAGKASATSG 372 Sterkiella nova
P29548   315 TTTGSKTKIPANPSPSGKKSTKTTDQMTMAQFKKYLDWHEKKKGGKTSSGGKVLGKRSAGKASATSG 381 Stylonychia mytilus
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