Conserved Protein Domain Family
RRM_LARP4
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cd12707: RRM_LARP4 (this model, PSSM-Id:241151 is obsolete and has been replaced by 410106)
RNA recognition motif in vertebrate La-related protein 4 (LARP4)
This subgroup corresponds to the RRM of LARP4, a cytoplasmic factor that can bind poly(A) RNA and interact with poly(A) binding protein (PABP). It may play a role in promoting translation by stabilizing mRNA. LARP4 is structurally related to the La autoantigen. Like other La-related proteins (LARPs) family members, LARP4 contains a La motif (LAM) and an RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Links
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Statistics
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PSSM-Id: 241151
Aligned: 4 rows
Threshold Bit Score: 167.538
Created: 10-Feb-2012
Updated: 1-Feb-2013
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q71RC2       199 CIVILREIPETTPIEEVKGLFksENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAIN 275 human
NP_001012718 199 CIIILREIPETTPVEEVKALFknENCPKVISCEFAHNNNWYVTFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAIN 275 chicken
NP_001091246 203 CIIILREIPETTPLEEVKALFdnENCPKVISCEFAHNNNWYVTFQSDTDAQQAFRYLREEVKTFQDKPIMARIKAIN 279 African clawed frog
XP_696696    217 CIIILREVPETTPVEEVEALFksEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAIN 293 zebrafish
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