12644351 1600 TNSCGMVAWCITVKTPEYPNGRKIIVVANDITF--QIGSFGPQEDEYFYKVTQLArQRGIpRIYLAANSGAR--IGVADE 1675 fission yeast 16126409 12 SDAFAKNAAHNRALVDELRAKVAQAALGGPESA--RERHTARGKLLPRERVERLL-DPGSpFLEVGQLAACDl---yNGE 85 Caulobacter cresc... 15806552 10 QAQPISSHSVWQGELARLRADQQQVRAGGGAKA--QQRQHDKGRLTARERVSKLI-DPGTpFDELMTFAGYGmyED-VGG 85 Deinococcus radio... 19703549 16 GKALANIDEANENAVKEIEAAIADSVAAMQDSGtsDEKIHDKGQMTALERVAELV-DEGT-WYPLNTLYNP------ENF 87 Fusobacterium nuc... 15840400 12 ASAYDEAAATMSGKLDEINAELAKALAGGGPKY--VDRHHARGKLTPRERIELLV-DPDSpFLELSPLAAYG-----SNF 83 Mycobacterium tub... 15842030 6 IAIAPSFADEHRRLVAELNNKLAAAALGGNERA--RKRHVSRGKLLPRERVDRLL-DPGSpFLELAPLAAGGm---yGDE 79 Mycobacterium tub... 15598084 12 GEDFARNREAMLAAVAGFR-ELEQKVLDKAAEA--RPKFEKRGQLLPRERLALLL-DPGApFLELSSLAGYKlhDDKDGT 87 Pseudomonas aerug... 15608114 10 ASAYDEAAATMSGKLDEINAELAKALAGGGPKY--VDRHHARGNLTPRERIELLV-DPDSpFLELSPLAAYG-----SNF 81 Mycobacterium tub... 15609639 6 IAIAPSFADEHRRLVAELNNKLAAAALGGNERA--RKRHVSRGKLLPRERVDRLL-DPGSpFLELAPLAAGGm---yGDE 79 Mycobacterium tub... 1705966 1559 ANAIGMVAFKITVKTPEYPRGRQFVVVANDITF--KIGSFGPQEDEFFNKVTEYArKRGIpRIYLAANSGAR--IGMAEE 1634 baker's yeast
12644351 1676 IVPLFNIAWVDPDSPEKGFDYIYLTPEAYERLQK-ENPNILTTEEVVTETGELRHKITTIIGSSEGLG---VECLRGSGL 1751 fission yeast 16126409 86 APGAGMICGVGRVSGREVMIVANDPTVKGGAYFPmTVKKHLRAQEIAAQNRLPCLYLVDSGGANLPHQaevFPDRDHFGR 165 Caulobacter cresc... 15806552 86 CPSGGTVTGIGQIGGRPWMIIANDATVKAGAFFPiTAKKVIRAQTIALENHLPTAYLVDSAGVYLPMQdeiFPDQDDFGR 165 Deinococcus radio... 19703549 88 ETGTGIVKGLGRIGGKWAVVVASDNKKIVGAWVPgQADNLLRASDTAKCLGIPLVYVLNCSGVKLDEQekvYANRRGGGT 167 Fusobacterium nuc... 15840400 84 QIGASLVTGIGAVCGVECMIVANDPTVKGGTSNPwTLRKILRANQIAFENRLPVISLVESGGADLPTQkeiFIPG---GQ 160 Mycobacterium tub... 15842030 80 SPGAGIITGIGRVSGRQCVIVANDATVKGGTYYPmTVKKHLRAQEVALQNMLPCIYLVDSGGAFLPRQdevFPDREHFGR 159 Mycobacterium tub... 15598084 88 QAGGGIIAGIGYIAGVRCLVSASNSAIKGGTISPtGLKKTLRLQQIAMENKLPVVTLTESGGANLNYAaeiFVEG---AR 164 Pseudomonas aerug... 15608114 82 QIGASLVTGIGAVCGVECMIVANDPTVKGGTSNPwTLRKILRANQIAFENRLPVISLVESGGADLPTQkeiFIPG---GQ 158 Mycobacterium tub... 15609639 80 SPGAGIITGIGRVSGRQCVIVANDATVKGGTYYPmTVKKHLRAQEVALQNMLPCIYLVDSGGAFLPRQdevFPDREHFGR 159 Mycobacterium tub... 1705966 1635 IVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKfDKENSVLTERTVIN-GEERFVIKTIIGSEDGLG---VECLRGSGL 1710 baker's yeast
12644351 1752 IAGVTSRAYND-IFTCTLVTCRAVGIGAYLVRLGQRAVQIEG---------------QPIILTGAPALNKVLGREVYTSn 1815 fission yeast 16126409 166 IFFNQARMSAAsIPQIACVMGSCTAGGAYVPAMSDETVIVRNq--------------GTIFLAGPPLVKAATGEVISAE- 230 Caulobacter cresc... 15806552 166 VFYLNARMSAAgIPQIAAIMGNCVAGGAYLPVMCDTLIMTEGs--------------G-LYLAGPALVKAAIGQVVDSE- 229 Deinococcus radio... 19703549 168 PFFRNAELQQLgIPVIVGIYGTNPAGGGYHSISPTILIAHKDanmavggagivggmnPKGYIDMEGAIQIAEATMAAKKv 247 Fusobacterium nuc... 15840400 161 MFRDLTRLSAAgIPTIALVFGNSTAGGAYVPGMSDHVVMIKEr--------------SKVFLAGPPLVKMATGEESDDE- 225 Mycobacterium tub... 15842030 160 IFYNQATMSAKgIPQVAAVLGSCTAGGAYVPAMSDEAVIVREq--------------GTIFLGGPPLVKAATGEIVSAE- 224 Mycobacterium tub... 15598084 165 GFANQARISAMgIPQVTVVHGSSTAGGAYQPGLSDYVVVVRGk--------------AKMFLAGPPLLKAATGEIASDE- 229 Pseudomonas aerug... 15608114 159 MFRDLTRLSAAgIPTIALVFGNSTAGGAYVPGMSDHVVMIKEr--------------SKVFLAGPPLVKMATGEESDDE- 223 Mycobacterium tub... 15609639 160 IFYNQATMSAKgIPQVAAVLGSCTAGGAYVPAMSDEAVIVREq--------------GTIFLGGPPLVKAATGEIVSAE- 224 Mycobacterium tub... 1705966 1711 IAGATSRAYHD-IFTITLVTCRSVGIGAYLVRLGQRAIQVEG---------------QPIILTGAPAINKMLGREVYTSn 1774 baker's yeast
12644351 1816 lQLGGTQVMHRN-GISHLTSQDDFDGISKIVNWISYIPDKRNNPVPISPSSDTWDRDVEFYPS-QNGYDPRWLIAGKEDE 1893 fission yeast 16126409 231 -ELGGAETHGRRsGVVDHVAENDEHALEIVRSIVANLNTTKPDQLVL-ADPEPPAYDPEELYG-IVPTDVRAPYDVREVI 307 Caulobacter cresc... 15806552 230 -DLGGASMHSAIaGTVDYKEKDDDAAINRLRALAELYAPAEPAPFAK-RRKETQDAPARDLTE-LVGFDSAKTYDVRDLI 306 Deinococcus radio... 19703549 248 eVPGTIHVHYDKtGFFREVYDDEIGVIDGIKKYMDYLPAYDLEFFRVD-EPTEPALDPNDLYS-IIPMNQKKIYNIYDVI 325 Fusobacterium nuc... 15840400 226 -SLGGAEMHARIsGLADYFALDELDAIRIGRRIVARLNWIKQGPAP--APVTEPLFDAEELIG-IVPPDLRIPFDPREVI 301 Mycobacterium tub... 15842030 225 -ELGGGDLHSRTsGVTDHLADDDEDALRIVRAIADTFGPCEPAQWDV-RRSVEPKYPQAELYD-VVPPDPRVPYDVHEVV 301 Mycobacterium tub... 15598084 230 -ELGGAELHAQVaGTAEYLAENDADGVRLAREIVGMLPWNAQLPARPARSWREPLYPVEELLG-VVPADPKKPYDVREIV 307 Pseudomonas aerug... 15608114 224 -SLGGAEMHARIsGLADYFALDELDAIRIGRRIVARLNWIKQGPAP--APVTEPLFDAEELIG-IVPPDLRIPFDPREVI 299 Mycobacterium tub... 15609639 225 -ELGGGDLHSRTsGVTDHLADDDEDALRIVRAIADTFGPCEPAQWDV-RRSVEPKYPQAELYD-VVPPDPRVPYDVHEVV 301 Mycobacterium tub... 1705966 1775 lQLGGTQIMYNN-GVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTnDETYDVRWMIEGRETE 1853 baker's yeast
12644351 1894 DS-FLyglFDkgSFQETLNGWAKTVVVGRARMGGIPTGVIAVETRtientvpadpanpdsteqvlmEAGQVWYPNSAFKT 1972 fission yeast 16126409 308 ARiVD---GS--QFDEFKALYGTTLVCGFARIWGQPVAILAN--------------------------NGVLFSESALKG 356 Caulobacter cresc... 15806552 307 KSlAD---GG--EFHEFKPEYGETIVCGFARAGGYPVAFVANQRTvikkklksg---gepglrtriEVGGVIYGDSADKA 378 Deinococcus radio... 19703549 326 GRlFD---NS--EFSEYKKGYGPEVVTGIAKVDGLLVGVIANAQGllmnype--------yrekavGIGGKLYRQGLIKM 392 Fusobacterium nuc... 15840400 302 ARiVD---GS--EFDEFKPLYGSSLVTGWARLHGYPLGILANA-------------------------RGVLFSEESQKA 351 Mycobacterium tub... 15842030 302 VRiVD---GS--EFSEFKAKYGKTLVTAFARVHGHPVGIVAN--------------------------NGVLFSESALKG 350 Mycobacterium tub... 15598084 308 ARiAD---GS--EFLDFKNEFDGQTVCGHLRIEGHACGLIGN--------------------------NGPITPQGAAKA 356 Pseudomonas aerug... 15608114 300 ARiVD---GS--EFDEFKPLYGSSLVTGWARLHGYPLGILANA-------------------------RGVLFSEESQKA 349 Mycobacterium tub... 15609639 302 VRiVD---GS--EFSEFKAKYGKTLVTAFARVHGHPVGIVAN--------------------------NGVLFSESALKG 350 Mycobacterium tub... 1705966 1854 SG-FEyglFDkgSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRtvenlipadpanpnsaetliqEPGQVWHPNSAFKT 1932 baker's yeast
12644351 1973 AQAInDFNHGEQLPLFILANWRGFSGGQRDMFNEVLKYGSYIVDALASYKQPVFVYIppFSELRGGSWVVVDPTINEd-Q 2051 fission yeast 16126409 357 AHFI-ELACKRKIPLIFLQNISGFMVGGKYEAGGIAKDGAKLVTAVASAEVPKFTVL--IGGSFGAGNYGMCGRAYS--P 431 Caulobacter cresc... 15806552 379 ARFI-LDANQAGVPLVFLSDVTGFMVGRDSEQEGIIRRGAKLVNAVSNSVVPKITII--TGGSFGAGNYAMNGKAYG--P 453 Deinococcus radio... 19703549 393 SEFV-TLCSRDRLPIVWLQDTSGIDVGNPAEEAELLGLGQSLIYSIENSHVPQIEIT--IRKGSAAAHYVLGGPQGNntN 469 Fusobacterium nuc... 15840400 352 TQFI-QLANRADTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLL--IGASYGAGHYGMCGRAYD--P 426 Mycobacterium tub... 15842030 351 AHFI-ELCDKRKIPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVV--IGGSYGAGNYSMCGRAYS--P 425 Mycobacterium tub... 15598084 357 AQFI-QLCEQSNTPLLFLHNTTGFMVGTESERQGVIKHGSKMIQAVANARVPKLTLV--VGGSYGAGNYAMCGRGLD--P 431 Pseudomonas aerug... 15608114 350 TQFI-QLANRADTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLL--IGASYGAGHYGMCGRAYD--P 424 Mycobacterium tub... 15609639 351 AHFI-ELCDKRKIPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVV--IGGSYGAGNYSMCGRAYS--P 425 Mycobacterium tub... 1705966 1933 AQAInDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIppTGELRGGSWVVVDPTINAd-Q 2011 baker's yeast
12644351 2052 MEMYADEESRAGVLEPEGMVSIKFRreKLLSLMRRCdhkyaSLCNELKRDDLSADDLSTIKVKLMEREQKLMPIYQQISI 2131 fission yeast 16126409 432 RFLFTWPNSRISVMGGEQAASVLAT--VHRDAAKw-----sPEEAEAFKAPIRQRYEDE-GNPYHATARLWDDGIIDPAQ 503 Caulobacter cresc... 15806552 454 RFIFAWPSAKYAVMSGNAAAKTLLD--IQLAALKRSghepdDEELTRLYDEVKSKYDTE-LDPRYAAARLWVDEIIEPND 530 Deinococcus radio... 19703549 470 AFSLGTAATEVYVMNGETAASAMYS--RRLAKDYKAgk--dLQPTIDKMNQLINEYTAK-SRPAYCAKTGMVDEIVPLYD 544 Fusobacterium nuc... 15840400 427 RFLFAWPSAKSAVMGGAQLSGVLSI--VARAAAEARgqqvdEAADAAMRAAVEGQIEAE-SLPLVLSGMLYDDGVIDPRD 503 Mycobacterium tub... 15842030 426 RFLWMWPNARISVMGGEQAASVLAT--VRGEQLSAAgtpwsPDEEEAFKAPIRAQYEDQ-GNPYYSTARLWDDGIIDPAD 502 Mycobacterium tub... 15598084 432 RFIFAWPNSRTAVMGGAQAGKVLRI--VTEEKHAKEgkeadPKMLEMLETVTAQKLDSQ-STALYGTASLWDDGLVDPRD 508 Pseudomonas aerug... 15608114 425 RFLFAWPSAKSAVMGGAQLSGVLSI--VARAAAEARgqqvdEAADAAMRAAVEGQIEAE-SLPLVLSGMLYDDGVIDPRD 501 Mycobacterium tub... 15609639 426 RFLWMWPNARISVMGGEQAASVLAT--VRGEQLSAAgtpwsPDEEEAFKAPIRAQYEDQ-GNPYYSTARLWDDGIIDPAD 502 Mycobacterium tub... 1705966 2012 MEMYADVNARAGVLEPQGMVGIKFRreKLLDTMNRLddkyrELRSQLSNKSLAPEVHQQISKQLADRERELLPIYGQISL 2091 baker's yeast
12644351 2132 HFADLHDRVGRMVAKKVVRKPLKWTEARRF 2161 fission yeast 16126409 504 TRDALGLAISASLNAPIPETT---FGVFRM 530 Caulobacter crescentus CB15 15806552 531 TRARLIRALEACAQNPRQEELR--VGVFQV 558 Deinococcus radiodurans 19703549 545 LRGYISAFANAVYQNPKSICAFHQMILPRA 574 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 15840400 504 TRTVLGMCLSAIANGPIKGTSN--FGVFRM 531 Mycobacterium tuberculosis CDC1551 15842030 503 TRTVVGLALSLCAHAPLDQVG---YGVFRM 529 Mycobacterium tuberculosis CDC1551 15598084 509 SRRLLGYLLDICAEAEARPLKGNSFGVARF 538 Pseudomonas aeruginosa PA01 15608114 502 TRTVLGMCLSAIANGPIKGTSN--FGVFRM 529 Mycobacterium tuberculosis H37Rv 15609639 503 TRTVVGLALSLCAHAPLDQVG---YGVFRM 529 Mycobacterium tuberculosis H37Rv 1705966 2092 QFADLHDRSSRMVAKGVISKELEWTEARRF 2121 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",