15827161 59 LPQIIQTALDGYAERPALGQRVAEFTKDPKT----G-RTSMEL-LPSFETITYRQLGDRVGALARAWRHD-L-------L 124 Mycobacterium leprae 19074698 26 CAPDGSKTIL-----ELLGARCASMGSDPFL----GtIVGSEV-KYRSAEDIWREAEGLAALFARLLAQE---------- 85 Encephalitozoon c... 19074700 108 CAPDGSKTIL-----ELLGARCASMGSDPFL----GtIVGSEV-KYRSAEDIWREAEGLAALFARLLAQE---------- 167 Encephalitozoon c... 15596814 1 ----------MVTANRLPLEVFFEREKRHPQ----RrYLVQPIgGGRVEELSWGEVGDQARRAAAWLRTLdLp------A 60 Pseudomonas aerug... 19112518 50 FGNKKAMGYRNLVKEHVETKMVTKVVDGEKKe--vPkSWSYFE-LSDYNYLSFNDIYDKALRYAGALRKLgL-------- 118 fission yeast 19112977 54 HGEKQAMGSRKLIKENREEREIIRKVDNEEVv--eKkLWTTYE-LGPYEYISFNKVYEIALALGSGLVASgIt------S 124 fission yeast 729924 81 SENLVSCVDKNLRTAYDHFMFSARRWPQRDClgsrPiDKATGTwEETFRFESYSTVSKRCHNIGSGILSLvNtkrkrplE 160 baker's yeast 729925 53 GGKRDGMAWRDVIEIHETKKTIVRKVDGKDKs--iEkTWLYYE-MSPYKMMTYQELIWVMHDMGRGLAKIgIk------P 123 baker's yeast 1346423 53 GGKRDGMAWRDIIDIHETKKTIVKRVDGKDKp--iEkTWLYYE-LTPYITMTYEEMICVMHDIGRGLIKIgVk------P 123 baker's yeast 266448 53 NKNSNAMGWRDVKEIHEESKSVMKKVDGKETs--vEkKWMYYE-LSHYHYNSFDQLTDIMHEIGRGLVKIgLk------P 123 baker's yeast
15827161 125 HaGYRVCVLGFNSVDYAIIDMALGVIGAVAVPLQTSAAITQLQSIVTETEPSMIATSVNQLPDTVELILSGQAPaklvVF 204 Mycobacterium leprae 19074698 86 ---DKVGIYSVNRYEWVVSEMASYMSGCINVPLYSTFSPADVRQILAETEMKVCVASADKAQLLLETVLEDSKAg----- 157 Encephalitozoon c... 19074700 168 ---DKVGIYSVNRYEWVVSEMASYMSGCINVPLYSTFSPADVRQILAETEMKVCVASADKAQLLLETVLEDSKAg----- 239 Encephalitozoon c... 15596814 61 G--SRIAIISKNCAHWIVTDLAIWMAGHVSVPLYPNLTAESARQVLEHSESAVVFVGKLDDWPAMAPGVP---------- 128 Pseudomonas aerug... 19112518 119 NkGDKFELYAPTSAFWLLTAEACLSQSMTIVTAYDTLGEEGLLHSLRESGVRGMYTEGHLLKTLVNPLKEIESLeviiYR 198 fission yeast 19112977 125 --ETTMLFFAATSAKWFTTAQGCSSQAIPIVTAYETLGEDGIYTSLDECKSRAIFTDPNLIPKLLGPLKQST------WV 196 fission yeast 729924 161 AnDFVVAILSHNNPEWILTDLACQAYSLTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVLKMVPDMKFVnt-lVC 239 baker's yeast 729925 124 NgEHKFHIFASTSHKWMKIFLGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIkfliHN 203 baker's yeast 1346423 124 NgENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTLGESGLIHSMVETDSVAIFTDNQLLSKLAVPLKTAKNVkfviHN 203 baker's yeast 266448 124 NdDDKLHLYAATSHKWMKMFLGAQSQGIPVVTAYDTLGEKGLIHSLVQTGSKAIFTDNSLLPSLIKPVQAAQDVkyiiHF 203 baker's yeast
15827161 205 DYHPEVD------EQHDAVATARARLADSSVVVESLTeVLGRGKTLPATpipvADDSADPLALLIYTSGSTGAPKGAMYL 278 Mycobacterium leprae 19074698 158 -LSCIVL------MDRDAGVAERLRNAG--VLVYYFGdVVSSGDKAGRK----RYPKGDDLATICYTSGTSGSPKGVMLT 224 Encephalitozoon c... 19074700 240 -LSCIVL------MDRDAGVAERLRNAG--VLVYYFGdVVSSGDKAGRK----RYPKGDDLATICYTSGTSGSPKGVMLT 306 Encephalitozoon c... 15596814 129 ----------------EGIPTVAMPLHPEGRFDRQWSdLQACAPLEGDT-----PTAAEQLATLIYTSGTTGVPKGVMHN 187 Pseudomonas aerug... 19112518 199 NDAKEED--------------IKTIQEIRPNLKLIKFaDFEKMSPpv----epDPPSPEEICCIMYTSGSTGLPKGVILS 260 fission yeast 19112977 197 KLIVCSS--------TPSEDLVELVKSTAPDVEIITYdNLLSLGKEKPQp--pHPPKADDICCYMYTSGSTGKPKGVVLL 266 fission yeast 729924 240 MDELTHD------ELRMLNESLLPVKCNSLNEKITFFsLEQVEQVGCFNkipaIPPTPDSLYTISFTSGTTGLPKGVEMS 313 baker's yeast 729925 204 EPIDPNDrrqngkLYKAAKDAINKIREVRPDIKIYSFeEVVKIGKKSKDevklHPPEPKDLACIMYTSGSISAPKGVVLT 283 baker's yeast 1346423 204 EPIDPSDkrqngkLYKAAKDAVDKIKEVRPDIKIYSFdEIIEIGKKAKDevelHFPKPEDPACIMYTSGSTGTPKGVVLT 283 baker's yeast 266448 204 DSISSEDrrqsgkIYQSAHDAINRIKEVRPDIKTFSFdDILKLGKESCNeidvHPPGKDDLCCIMYTSGSTGEPKGVVLK 283 baker's yeast
15827161 279 Q----SNVGKMWRRSDgnwfgPT-AASITLNFMPMSHVMGRG-Il----yGTLGNGGTAYFAARSDLSTLLEDLKLVRPT 348 Mycobacterium leprae 19074698 225 HrnfvSCVAGISRGSRagemvEIgRDDVYLSYLPLAHVMER--Vc----mNISMASGCRIVFFRGNLKEIKEDYLVVRPT 298 Encephalitozoon c... 19074700 307 HrnfvSCVAGISRGSRagemvEIgRDDVYLSYLPLAHVMER--Vc----mNISMASGCRIVFFRGNLKEIKEDYLVVRPT 380 Encephalitozoon c... 15596814 188 FssfaFAASRGVELFG------TrEDDRMLSYLPLCHVAERMfV------EMGSLYGGTTVFFAESLDTFVEDMKRARPT 255 Pseudomonas aerug... 19112518 261 HknmvAIVTAIVKHVP-----EVtSKDYLLAYLPLAHILEFAfEniclawGGTIGYANVRTLVDTNCRNCKGDINTFRPT 335 fission yeast 19112977 267 HrniiAALGGINRILSq----HInVKDYVLAYLPLAHIFEFIfEmcclywGGVLGYASPRTLTDASVVNCKGDLTEFRPT 342 fission yeast 729924 314 HrniaSGIAFAFSTFRip-pdKRnQQLYDMCFLPLAHIFERMvIa-----YDLAIGFGIGFLHKPDPTVLVEDLKILKPY 387 baker's yeast 729925 284 HynivSGIAGVGHNVFg----WIgSTDRVLSFLPLAHIFELVfEfeafywNGILGYGSVKTLTNTSTRNCKGDLVEFKPT 359 baker's yeast 1346423 284 HynivAGIGGVGHNVIg----WIgPTDRIIAFLPLAHIFELTfEfeafywNGILGYANVKTLTPTSTRNCQGDLMEFKPT 359 baker's yeast 266448 284 HsnvvAGVGGASLNVLk----FVgNTDRVICFLPLAHIFELVfEllsfywGACIGYATVKTLTSSSVRNCQGDLQEFKPT 359 baker's yeast
15827161 349 ELNFVPRIWETLYDESKRAVDRRLANSGSADRAAIKAEVM----DEQR------------------QSLLG-GRYIAAMT 405 Mycobacterium leprae 19074698 299 FIIAVPRVLNLFKEKIEEKVQQKNFAARCAFRGALWYKMWrvskGELRsrfvdw------lvfdriAKEFG-GRINRILC 371 Encephalitozoon c... 19074700 381 FIIAVPRVLNLFKEKIEEKVQQKNFAARCAFRGALWYKMWrvskGELRsrfvdw------lvfdriAKEFG-GRINRILC 453 Encephalitozoon c... 15596814 256 LLFGVPRIWTKFQMGVYSKMPAQKLDR--LLKLPILGrivg----------------------rkvLAGLGlDAVRYALC 311 Pseudomonas aerug... 19112518 336 IMVGVPAVWEMVRKGIMSKLNAASAVKRSVFWTAYYTKAKlmrhNLPGscvldt------avfnkiRSMGTgGRLRYTLS 409 fission yeast 19112977 343 VLIGVPAVYELIKKGILAKVSSMPAHRQKVFSGSLSLKQYlierNLPGsaalda------ivfnkvKAATG-GRLRYCIS 415 fission yeast 729924 388 AVALVPRILTRFEAGIKNALDKSTVQRN-VANTILDSKSArftaRGGPdksimnflvyhrvlidkiRDSLGlSNNSFIIT 466 baker's yeast 729925 360 IMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAY----SmkekSVPCtgflsr------mvfkkvR-QATgGHLKYIMN 428 baker's yeast 1346423 360 VMVGVAAVWETVRKGILAKINELPGWSQTLFWTVY----AlkerNIPCsgllsg------lifkriR-EATgGNLRFILN 428 baker's yeast 266448 360 IMVGVAAVWETVRKGILNQIDNLPFLTKKIFWTAYNTKLNmqrlHIPGggalgn------lvfkkiR-TATgGQLRYLLN 432 baker's yeast
15827161 406 GSAPTSPELKHGVESLLeMHLLEGYGSTE---AGMVL-FDGEVQR------P-PVIDYKLVDvpdlgyf---stdqpypR 471 Mycobacterium leprae 19074698 372 GSAPLRREVLVYMQAVLsCRIFQGYGQTEnvgAGIVQpLDSRVYDnv--giPfPANEVNLGEipeelgseymrrypgcrV 449 Encephalitozoon c... 19074700 454 GSAPLRREVLVYMQAVLsCRIFQGYGQTEnvgAGIVQpLDSRVYDnv--giPfPANEVNLGEipeelgseymrrypgcrV 531 Encephalitozoon c... 15596814 312 GAAPVPEALLLWYRRLG-LDVLEVYGMTEnsgYSHVCrPGRQKTGwi--gqNsPGVEVRISD-----------------E 371 Pseudomonas aerug... 19112518 410 GGSALSPDTKRFLSIVL-CPMLIGYGLTEisaAAMVQnPACFNLDdsa-gsLlPCTEMKLVDceegnyn----shghppR 483 fission yeast 19112977 416 GGAALAASTQAFLSSCI-CPVLPGYGLTEtcaGSFVLsPEQWHLYantvgfPiPSIEFKLVDipdlgyy----tdssppR 490 fission yeast 729924 467 GSAPISKDTLLFLRSALdIGIRQGYGLTEtfaGVCLSePFEKDVGsc--gaIgISAECRLKSvpemgy-----hadkdlK 539 baker's yeast 729925 429 GGSAISIDAQKFFSIVL-CPMIIGYGLTEtvaNACVLePDHFEYGiv--gdLvGSVTAKLVDvkdlgy------yaknnQ 499 baker's yeast 1346423 429 GGSAISIDAQKFLSNLL-CPMLIGYGLTEgvaNACVLePEHFDYGia--gdLvGTITAKLVDvedlgy------faknnQ 499 baker's yeast 266448 433 GGSPISRDAQEFITNLI-CPMLIGYGLTEtcaSTTILdPANFELGva--gdLtGCVTVKLVDveelgy------faknnQ 503 baker's yeast
15827161 472 GELLLKTQNMFPGYYKRPEVTATVFDSDGYYQTGDI-VAEVGpDRLVYVDRRNNVLKLAQGQFVTVAKLEA-AFSNSPLV 549 Mycobacterium leprae 19074698 450 GEILLRGDNVTQGYYKRPKETGQLFTKDGWLRTGDIgMFDSSaGVFSVIGRVKDGFKTSQGEYIDPEKLEV-LYADGDVV 528 Encephalitozoon c... 19074700 532 GEILLRGDNVTQGYYKRPKETGQLFTKDGWLRTGDIgMFDSSaGVFSVIGRVKDGFKTSQGEYIDPEKLEV-LYADGDVV 610 Encephalitozoon c... 15596814 372 GEVQVRSGATMVGYYKEPEKTAEVLTADGFLRTGDKgEQDAD-GNLRLTGRMKEIFKTSKGKYVAPAPIEN-RLAVHDRI 449 Pseudomonas aerug... 19112518 484 GEIWLRGPSLTRGYLNRDKENKESFTPDGWFRTGDVgELTPE-GLLRIIDRKKNLVKTQNGEYIALEKLES-RYRTSSLV 561 fission yeast 19112977 491 GEVWIRGPAVCNGYLNRPEDNKAAFTEDGWFKTGDVgEIAKG-NTLRLIDRKKNIVKSLNGEYIALEKIEA-QFFTSPLV 568 fission yeast 729924 540 GELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVaFIDGK-GRISVIDRVKNFFKLAHGEYIAPEKIENiYLSSCPYI 618 baker's yeast 729925 500 GELLLKGAPVCSEYYKNPIETAVSFTYDGWFRTGDIvEWTPK-GQLKIIDRRKNLVKTLNGEYIALEKLES-VYRSNSYV 577 baker's yeast 1346423 500 GELLFKGAPICSEYYKNPEETAAAFTDDGWFRTGDIaEWTPK-GQVKIIDRKKNLVKTLNGEYIALEKLES-IYRSNPYV 577 baker's yeast 266448 504 GEVWITGANVTPEYYKNEEETSQALTSDGWFKTGDIgEWEAN-GHLKIIDRKKNLVKTMNGEYIALEKLES-VYRSNEYV 581 baker's yeast
15827161 550 RQIYIYGnSAHPYLLAVVVPTEDALAt----NDIEVLKPLII----DSLQKVAKEADLQSYEVPRDLIVETTP--FSLEN 619 Mycobacterium leprae 19074698 529 QDVCIPRrSDSDRIVAIVVCPETKKS------DAEILAHVR-----ETGEKLFKQRRITRLEIPWRVVVLRRG--FESFE 595 Encephalitozoon c... 19074700 611 QDVCIPRrSDSDRIVAIVVCPETKKS------DAEILAHVR-----ETGEKLFKQRRITRLEIPWRVVVLRRG--FESFE 677 Encephalitozoon c... 15596814 450 EQVCVVG---EGLSAPLGLCVLSEVG------RREALN----------G-TRGALESSLRAHLEQVNGALDKH-----ER 504 Pseudomonas aerug... 19112518 562 SNICVYAdQTKVKPLAIIVPNEPVVRkl-atEQAGLSPDA-------SWEEVCHNKKVRQLVYDDLIRIGRSHhfANIEL 633 fission yeast 19112977 569 SNVCAYAdVNHAKPVVIVNPDENGLRtyltkNSGSSFNGNPN----DTLTNLCKDSGVQHLILKELINIGKQQrlASIEI 644 fission yeast 729924 619 TQIFVFGdPLKTFLVGIVGVDVDAAQp----ILAAKHPEVKTwtkeVLVENLNRNKKLRKEFLNKINKCTDGL--QGFEK 692 baker's yeast 729925 578 KNICVYAdESRVKPVGIVVPNPGPLSkf-avKLRIMKKGE-------DIENYIHDKALRNAVFKEMIATAKSQglVGIEL 649 baker's yeast 1346423 578 QNICVYAdENKVKPVGIVVPNLGHLSkl-aiELGIMVPGE-------DVESYIHEKKLQDAVCKDMLSTAKSQglNGIEL 649 baker's yeast 266448 582 ANICVYAdQSKTKPVGIIVPNHAPLTkl-akKLGIMEQKDSS----INIENYLEDAKLIKAVYSDLLKTGKDQglVGIEL 656 baker's yeast
15827161 620 G--LLTGIRKLAWPKLKQHYGARLEQLYADLVEGQANALHVLKQSVA 664 Mycobacterium leprae 19074698 596 GadLLTPTAKKRRPLIERYFSQEIDSLLGIK---------------- 626 Encephalitozoon cuniculi 19074700 678 GadLLTPTAKKRRPLIERYFSQEIDSLLGIK---------------- 708 Encephalitozoon cuniculi 15596814 505 LvgLVLVQETWAVDNGFLTPTLKIKRNMVEGAYGSRFHEWVERREAV 551 Pseudomonas aeruginosa PA01 19112518 634 IqnVVLVPIEFTPENGLVTAAQKLQRRKILDRFKKEIDAAYAE---- 676 fission yeast 19112977 645 PegVVLSDFEWTAENNFLTASRKVKRQVIVAHYSDEIQKAYSKKH-- 689 fission yeast 729924 693 LhnIKVGLEPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLYAEGSLV 739 baker's yeast 729925 650 LcgIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVYKENS-- 694 baker's yeast 1346423 650 LcgIVFFEEEWTPENGLVTSAQKLKRRDILAAVKPDVERVYKENT-- 694 baker's yeast 266448 657 LagIVFFDGEWTPQNGFVTSAQKLKRKDILNAVKDKVDAVYSSS--- 700 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",