2Q0Z_X              12 DVAPLNLGXIAAYY---YINYTTIELFSXSLN-AKTKVRGLIEIISNAAEYE---------NIPIRHHEDNLLRQLAQKV 78   human
O60072            1615 TYAPTTLGRIVSYY---YLFHTTIRNFVQKIT-ENAEFDLALQLLAEASEFD---------DLAIRHNEDLINIEINKSL 1681 Schizosa...
AAF55204          1444 CLIPTFLGRISSYY---YLSYRTMKHFLEDLQ-PGMNTKKVLLAIADSYEFD---------QLPVRHNEDKHNEEMAEVS 1510 Drosophi...
FlyBase:CG8583-PA  211 GVWWYRSIRFSGDKv--LLDTTQMYFYFIHKT-PHMLLKRALMVLAASLEFDkrhnsqvqeRQSDNDEVPALIRQLPNLN 287  fruit fly
AAG45474          1533 SIEPLTYGRIASYY---YLKHQTVKMFKDRLK-PECSTEELLSILSDAEEYT---------DLPVRHNEDHMNSELAKCL 1599 human
CAY80030          1623 DIVATPFLSISSYY---YISHLTIRQLLKQIH-DHATFQEVLRWLSLAVEYN---------ELPVRGGEIIMNEEMSQQS 1689 Saccharo...
NP_011263          613 EYKSTAYGNAMTRH---YISFESMKQFINAKK--FLSLQGILNLLATSEEFS---------VMRVRHNEKKLFKEINLSP 678  Saccharo...
EGA76745            72 SRWWARTQSYTKKGihnVTASNFVSNLVNYKPsEIVTTDLILHWLSFAHEFK---------Q-----FFPDLQPTDFEK- 136  Saccharo...
NP_493463          212 GMWWYSSIKYSADKv--LLDTTRMYYYFINRT-PRMEIGRMIAVLSGSFEFSkqynkeiqeRETDDYEVPRLMKQIAGVN 288  nematode
CAB70701            81 GSWWYRSIRYSGDQi--LIRTTQIYTYFVYKT-RNMDMKRLIMVLAGASEFDpqynkdatsRPTDNILIPQLIREIGSIN 157  human

2Q0Z_X              79 PHKLNn-------PKFNDPHVKTNLLLQAHLSRx---------QLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSP- 141  human
O60072            1682 KYSAAcl-----nLPMVDAHVKAFILTQAHMARl--------kLPVDDYVTDTSTVLDQVIRIIQSYIDVSAELGYSHV- 1747 Schizosa...
AAF55204          1511 RFRPPs-------SSWDSSYTKTFLLLQAHFARq--------sLPNSDYLTDTKSALDNATRVMQAMVDYTAERGWLST- 1574 Drosophi...
FlyBase:CG8583-PA  288 EKCKEh-------PLCRMYSIKARAILHAHLSRm--------pLNPETLERDRQFVVKKCPYLVQEMVSCVHQLVMMAYa 352  fruit fly
AAG45474          1600 PIESNp-------HSFDSPHTKAHLLLQAHLSRa--------mLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVT- 1663 human
CAY80030          1690 RYSVEstftdefeLPMWDPHVKTFLLLQAHLSRv--------dLPIADYIQDTVSVLDQSLRILQAYIDVASELGYFHT- 1760 Saccharo...
NP_011263          679 LLKYPfltekkqsQIIDRVSQKVSLLIQYELGGlefpsyegasKLHQTLVQDKFLVFRHCFRLLKCMVDTFIEKSDGTS- 757  Saccharo...
EGA76745           137 -------------------------LLQDHINRr----------DSGKLNNAKFRIVAKCHSLLHGLLDIACGFRNLDI- 180  Saccharo...
NP_493463          289 DKGKEq-------PLSQPYALKSRVLLHAYLSRlp------leSQNDALEEDQSYIITRILRFVEEMVNCSQNLMNYSQh 355  nematode
CAB70701           158 LKKNEp-------PLTCPYSLKARVLLLSHLARm---------KIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARn 221  human

2Q0Z_X             142 -------------ALAAXELAQXVTQAXWS-K-DSYLKQLPHFTSEHIKRCTDk--------G----------VESVFDI 188  human
O60072            1748 -------------CLQYISLMQCLKQACYP-S-EIYRASLPGLNASSEKEARD--------------------YLNKFAG 1792 Schizosa...
AAF55204          1575 -------------TLVVQQLMQSVIQARWF-D-GSEFLTLPGVNEDNLDAFLNiph---ddyD----------YLTLPVL 1626 Drosophi...
FlyBase:CG8583-PA  353 rrvpr--lpsietIENCMKMSPMIIQGLWE-F-KSPLLQLPHLTEDHLYFMNKk-------rH----------VKNLQQF 411  fruit fly
AAG45474          1664 -------------VLNITNLIQMVIQGRWL-K-DSSLLTLPNIENHHLHLFKKw--------KpimkgphargRTSIECL 1720 human
CAY80030          1761 -------------VLTMIKMMQCIKQGYWY-E-DDPVSVLPGLQLRRIKDYTFseqgfiemtP----------QQKKKKL 1815 Saccharo...
NP_011263          758 -------------LKNTLFLLRSLNGHCWEnT-PMVLRQLKTIGLVSVRRLIRh--------G----------ITNLEEM 805  Saccharo...
EGA76745           181 -------------ALGAINTFKCIVQAVPL-TpNCQILQLPNVDKEHFITKTg---------D----------IHTLGKL 227  Saccharo...
NP_493463          356 tki------sietFDNLLKLQPMFVQALWQ-K-NSPLLQLPHITDYNLQHLRKk--------R----------VFSCHDL 409  nematode
CAB70701           222 reerefraptlasLENCMKLSQMAVQGLQQ-F-KSPLLQLPHIEEDNLRRVSNhk-----kyK----------IKTIQDL 284  human

2Q0Z_X             189 XEX-EDE--ERNALLQLTd------SQ------------IADVARFCNRYPNIELSYEV-----VDK-----DSIRS-GG 236  human
O60072            1793 NKT-D-E--LYQMLCNDPn-----vFD------------IESLVNSLISYPKMNIEVSQ-----SSS------DKLL-LY 1839 Schizosa...
AAF55204          1627 KEL-CKQ--EYEVLAKPLrda-feeHE------------IEKMYKVIQDLPEIAIQIFV-----EGRh---mENEYA-KR 1681 Drosophi...
FlyBase:CG8583-PA  412 AQL-KPE--ESRQLLKNLs-----dFE------------YENTMKVLGKMPLIDFSIRC-----EVIddentNVVTA-GA 465  fruit fly
AAG45474          1721 PEL-IHAcgGKDHVFSSMveselhaAK------------TKQAWNFLSHLPVINVGISV-----KGSw----DDLVE-GH 1777 human
CAY80030          1816 LTLeEIG--RFGYKKLLNv------FDqltfgmtesedtKKRFVSVCQRLPVLEGMKFE-----EQE-----NNEVLtFY 1877 Saccharo...
NP_011263          806 GHL-SDT--QIEYYLNLKi------GN------------GIKIKNDISLLPCLNIRTKL-----ENC-----KIENE-EL 853  Saccharo...
EGA76745           228 FTL-EDA--KIGEVLGIKd-----qAK------------LNETLRVASHIPNLKIIKADflvpgENQ-----VTPSS-TP 281  Saccharo...
NP_493463          410 AVM-DAE--TRRSVLRSLs-----nEE------------YRDVMVVLSMMPRLQIETKT-----VVEgeddkHELTA-GC 463  nematode
CAB70701           285 VSL-KES--DRHTLLHFLe-----dEK------------YEEVMAVLGSFPYVTMDIKS-----QVLddedsNNITV-GS 338  human

2Q0Z_X             237 PVVVLVQLEREEEvtgpvia------------------------------------------------------------ 256  human
O60072            1840 LRRLNQPLNPDfyifap--------------------------------------------------------------- 1856 Schizosa...
AAF55204          1682 PLSLSDDTRGEWMslhanedyvlivnlqrlnvsg---------------------------------------------- 1715 Drosophi...
FlyBase:CG8583-PA  466 IVTVTVTLERKDMktlfgdtkapekqgikdetneeaagdedeaaaaapvkkasawakprkggkgkggkkpaqnqknqkkv 545  fruit fly
AAG45474          1778 NELSVSTLTADKRddnkwiklhadqeyvlqvslqrv-------------------------------------------- 1813 human
CAY80030          1878 SKHLSSKHNNGFEvycdk-------------------------------------------------------------- 1895 Saccharo...
NP_011263          854 WLTFKVEISATFKssiwhgqhl---------------------------------------------------------- 875  Saccharo...
EGA76745           282 YISLKVLVRSAKQpl----------------------------------------------------------------- 296  Saccharo...
NP_493463          464 VVTLKVTMRRSRLidpqeagladqykkyaedggddeleaseapeeaaatveeeevkkrkpweknkpkqkkkkaqgqgqkk 543  nematode
CAB70701           339 LVTVLVKLTRQTMaevfekeqsicaaeeqpaedgqgetnknrtkggwqqkskgpkktakskkkkplkkkptpvllpqskq 418  human

2Q0Z_X                 --------------------------------------------------------------------------------      human
O60072                 --------------------------------------------------------------------------------      Schizosa...
AAF55204               --------------------------------------------------------------------------------      Drosophi...
FlyBase:CG8583-PA  546 pakaattatitased-----qaaagnsdaeseagnadgsdvesaagsgsedeekgknnssldddddeewerlqaklnkre 620  fruit fly
AAG45474          1814 -------------------------------------------------------------------------------h 1814 human
CAY80030               --------------------------------------------------------------------------------      Saccharo...
NP_011263              --------------------------------------------------------------------------------      Saccharo...
EGA76745               --------------------------------------------------------------------------------      Saccharo...
NP_493463          544 fvkknapaspdtekal---keeakeeddddeknskasdsedeesgasdsekdgaaaaggdqkddqtdseweddvanskks 620  nematode
CAB70701           419 qkqkqangvvgneaavkedeeevsdkgsdseeeetnrdsqsekddgsdrdsdreqdekqnkddeaewqelqqsiqrkera 498  human

2Q0Z_X             257 --------------plfpqkrE--------------------------------------------EGWWVVIGDAKSN- 277  human
O60072            1857 ---------------lfpkpqS--------------------------------------------EGFFVLIIDSETQ- 1876 Schizosa...
AAF55204          1716 -qrrgggqsytvhcpkypkpkN--------------------------------------------EAWFLTLGSQAND- 1749 Drosophi...
FlyBase:CG8583-PA  621 rlegksrlshtvhcpyfpeekQ--------------------------------------------EYWWTYICDRKSR- 655  fruit fly
AAG45474          1815 fgfhkgkpescavtprfpkskD--------------------------------------------EGWFLILGEVDKR- 1849 human
CAY80030          1896 -----------------fpkiQ--------------------------------------------KELWFLIGH-KGD- 1912 Saccharo...
NP_011263          876 -------------sldietekS--------------------------------------------SGELIDFRRLQVN- 897  Saccharo...
EGA76745           297 -------------------ipTslipeenltepqdfesqrdpfammskqplvpysfapffptkrrgSWCCLVSSQKDGKi 357  Saccharo...
NP_493463          621 ifetkntqthtvhapffptekF--------------------------------------------EWWWITVAYVDKKe 656  nematode
CAB70701           499 lletkskithpvyslyfpeekQ--------------------------------------------EWWWLYIADRKEQ- 533  human

2Q0Z_X             278 ---SLISIKRLTLQQKA------------------------------KVKLDFVAPATGA--HNyTLYFXSDAY-XGCDQ 321  human
O60072            1877 ---ELFAIRRASFAGRRndds-----------------------irlSLRISMDIPPTCRn-RNvKVMVVCDGY-PLIYE 1928 Schizosa...
AAF55204          1750 ---ELLAMKRVSIRGQRc-----------------------------TNRISFQATPRLGr-LQlTLYLMSDCL-MGFDQ 1795 Drosophi...
FlyBase:CG8583-PA  656 ---TLLTAPYHVTNLVEk----------------------------eEIQLKFTAPRWPGv-YTfTVCLRSDSY-LGMDQ 702  fruit fly
AAG45474          1850 ---ELIALKRVGYIRNHh-----------------------------VASLSFYTPEIPGr-YIyTLYFMSDCY-LGLDQ 1895 human
CAY80030          1913 ---ELLMIKRCQPKQMNke---------------------------vIIHCDLFIPEEIRg-EElQFSLINDAL-GLRYD 1960 Saccharo...
NP_011263          898 ---KLQSPRGFRISAKIsp---------------------------kLEKIEFSIHCQEIagLGkTIVYSTDHL-ASQFS 946  Saccharo...
EGA76745           358 l-qTPIIIEKLSYKNLNddkdffdkrikmdltkhekfdindweigtiKIPLGQPAPETVGdfFFrVIVKSTDYFtTDLDI 436  Saccharo...
NP_493463          657 ksrQLLTFPQLVKTLIDe----------------------------qTIDIRFAAPPHKGi-YTyNLSVKSDSY-MDAEY 706  nematode
CAB70701           534 ---TLISMPYHVCTLKDt----------------------------eEVELKFPAPGKPGn-YQyTVFLRSDSY-MGLDQ 580  human

2Q0Z_X             322 EYKFSVD 328  human
O60072            1929 HKIVLMI 1935 Schizosaccharomyces pombe 972h-
AAF55204          1796 QYDLQFE 1802 Drosophila melanogaster
FlyBase:CG8583-PA  703 QQELKLD 709  fruit fly
AAG45474          1896 QYDNLSQ 1902 human
CAY80030          1961 MVHKLIS 1967 Saccharomyces cerevisiae EC1118
NP_011263          947 AKTPNIR 953  Saccharomyces cerevisiae S288c
EGA76745           437 TMNMKVR 443  Saccharomyces cerevisiae Vin13
NP_493463          707 SVDFKID 713  nematode
CAB70701           581 IKPLKLE 587  human