1GGU,1L9M,1X3Z


Conserved Protein Domain Family
TGc

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smart00460: TGc 
Transglutaminase/protease-like homologues
Transglutaminases are enzymes that establish covalent links between proteins. A subset of transglutaminase homologues appear to catalyse the reverse reaction, the hydrolysis of peptide bonds. Proteins with this domain are both extracellular and intracellular, and it is likely that the eukaryotic intracellular proteins are involved in signalling events.
Statistics
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PSSM-Id: 214673
Aligned: 47 rows
Threshold Bit Score: 36.2067
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GGU_B    293 ENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQmdifleedgnvnskltkdSVWNYHCWNEAWM--Trp 370 human
CAA21253  155 LLDSRKGRCGEWANCFTFLCRALGSRARWIWN--------------------------------AEDHVWTEVYS--Nk- 199 fission yeast
AAB91309  108 IAYFKVGGCGELARLFCEAAKRAGFEARVVSDL-------------------------------GYDHAWVEVKI--N-- 152 Archaeoglobus fulg...
Q02890    183 LLETRKGRCGEWCNLFTLILKSFGLDVRYVWN--------------------------------REDHVWCEYFS--Nf- 227 Saccharomyces cere...
O87990    157 CLDGGFGICGNHQYLFLELMHRLGLEARSVGFWYIDPNAN-----------------------SRASHAAAEVLV--D-- 209 Bordetella bronchi...
CAY78391  516 ILYRKHCTPYELTWLFKKLANSLGITCEIVIGFLKTPSAINW--------------------EFKYNHCWLRILV--N-- 571 Saccharomyces cere...
NP_593561 528 VISEGQGTPFEVALLVKEMLQALDLWCEVIEGYLKSPDDIYYTR------------------DININHAWNVVTF--D-- 585 Schizosaccharomyce...
NP_440113 190 VLARGETICSGYSNLYQALAKELGLDVVIIEGFAKGGDVIVGD-------------------DPDVNHAWNGVKI--D-- 246 Synechocystis sp. ...
1X3Z_A    176 LLETRKGRCGEWCNLFTLILKSFGLDVRYVWN--------------------------------REDHVWCEYFS--Nf- 220 baker's yeast
AAF74721  179 LLQTRTGRCGEWANCFGLLLAALNLESRFIY--------------------------------DTTDHVWNEVYLlaE-- 224 nematode
1GGU_B    371 dlpvgfGGWQAVDSTP 386 human
CAA21253  200 -----qQRWVHVDSGE 210 fission yeast
AAB91309  153 ------NSWVVADPTV 162 Archaeoglobus fulgidus DSM 4304
Q02890    228 -----lNRWVHVDSCE 238 Saccharomyces cerevisiae S288c
O87990    210 ------KKWRYVDITW 219 Bordetella bronchiseptica
CAY78391  572 ------KEWRFIDVIL 581 Saccharomyces cerevisiae EC1118
NP_593561 586 ------NEVRLIDASF 595 Schizosaccharomyces pombe 972h-
NP_440113 247 ------GQWYLLDTTW 256 Synechocystis sp. PCC 6803
1X3Z_A    221 -----lNRWVHVDSCe 231 baker's yeast
AAF74721  225 ------QRWCHVDPCe 234 nematode
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