1TYE_B      12 SCQQCLAV-SpMCAWCSDEALP--LG---SPRCDLKENLLkdncAPESIEFPVS--EARVLEDRPLSD----------K- 72   human
Q27874      49 TCSACIQYhE-SCAWCGAPMFD--EKk-pYARCDSRAKLMehgcPNSYIEDPAT--KLDITEDSKLSDqg-------qV- 114  Caenorhabditis e...
P92163      35 TCGECISLdS-SCGWCTLLNYT--DDt-gNPQCDLASSLSqrgcS--QIVDPDS---TMVLGWISLSNa--------gS- 96   Strongylocentrot...
Q27591      38 SCERCLSAhL-ECAWCTDKEYQ--VG----YRCLSRRQLLnyncSETDIYENQp--VLDVLQDKPLKD----------Y- 97   fruit fly
P91774      40 KCVDCIQT-P-DCMWCSKLKNE--SEq-rVARCQHIRADP----PPSAAPDHLEniTNSVFITQDTPLtvagnenrgtT- 109  signal crayfish
CAL38675    30 TCEDCLLI-GpQCAWCAQENFThpSGv--GERCDTPANLLakgcQLNFIENPVS--QVEILKNKPLSV----------Gr 94   synthetic construct
NP_002205   54 SCARCLAL-GpECGWCVQEDFI--SGgsrSERCDIVSNLIskgcSVDSIEYPS------VHVIIPTEN------------ 112  human
NP_524793   45 KCHTCIQTe--GCAWCMQPDFK--GQ----SRCYQNTSSLc---PEEFAYSPIT--VEQILVNNKLTN----------Q- 100  fruit fly
AAB66910    31 KCNQCI-G-EaNCAWCSDKDFG-------SSRCDSQKILElngcS--NISNPKS--ESKIQQDS---------------- 81   Acropora millepora
CAB61345    36 SCTECVRV-DkDCAYCTDEMFR--DR-----RCNTQAELLaagcQRESIVVMES--SFQITEETQID------------- 92   human

1TYE_B      73 -G-----------------------------------------------SGDssQVTQVSPQRIALRLRPDDSKNFSIQV 104  human
Q27874     115 -E-----------------------------------------------SEE--EAVQIKPQEMYVEIRPKSRVRFNVTY 144  Caenorhabditis e...
P92163      97 -A-----------------------------------------------PQG--QAVQVRPQQVDLKLRRGKPVVMTLPG 126  Strongylocentrot...
Q27591      98 -E-----------------------------------------------TSD--QAVQVTPQRAYLKLVKGNTQRMKLSY 127  fruit fly
P91774     110 -G-----------------------------------------------EAD--KIVQLKPQRMKLKLRKGVPINITLTY 139  signal crayfish
CAL38675    95 qK-----------------------------------------------NSS--DIVQIAPQSLILKLRPGGAQTLQVHV 125  synthetic construct
NP_002205  113 ---------------------------------------------------E--INTQVTPGEVSIQLRPGAEANFMLKV 139  human
NP_524793  101 -YkaelaaggggsamsgsssssyssssssssfysqsssgsssasgyeeySAG--EIVQIQPQSMRLALRVNEKHNIKISY 177  fruit fly
AAB66910    82 -------------------------------------------------NVG--AKVQVQPKKIRLNLRAGNPAKFTLTV 110  Acropora millepora
CAB61345    93 -------------------------------------------------TTL--RRSQMSPQGLRVRLRPGEERHFELEV 121  human

1TYE_B     105 RQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPpEALENPCYDmkttC 184  human
Q27874     145 RQAVDYPVDLYYLMDLSYSMKDDKQKLSELGDLLAERMRTVTKNFRLGFGSFIDKKLMPFIDPRI-EKQLSPCPTp---C 220  Caenorhabditis e...
P92163     127 PTAEDYPVDLYYVMDLSKSMEDDLSKLMDLGDILASEMKNITSNFRLGFGSFVDKTVMPYVSTVP-EKLIAPCTG----C 201  Strongylocentrot...
Q27591     128 RTARNNPLDLYVLMDLTWTMRDDKKTLEELGAQLSQTLKNLTGNYRLGFGSFADKPTLPMI--LP-QHRENPCAAeratC 204  fruit fly
P91774     140 RQARDYPVDLYYLMDLSNSMSDDKKQLAALGSELAKLMKGLTSQFTLGFGSFVDKVLMPYADTSP-QKLLQPCPG----C 214  signal crayfish
CAL38675   126 RQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTP-EEIANPCSSipyfC 204  synthetic construct
NP_002205  140 HPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHP-ERIHNQCSDynldC 218  human
NP_524793  178 SQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIP-KKLEHPCEN----C 252  fruit fly
AAB66910   111 RPAENYPVDLYYLMDMSSSMKDDLGNLRSLAGQMATTMKEITSNFKLGFGSFVDKAVSPFVRT----ELKLPCDNn--sC 184  Acropora millepora
CAB61345   122 FEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRP-EKLKEPWPN----S 196  human

1TYE_B     185 LPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNd--ASHLLVFTTDAKTHIALDGR- 261  human
Q27874     221 AEPYGFKHQMSLTTNTAKFKAEVDKAEISGNLDAPEGGFDAVVQALACNKTIGWREr--ARKMIVFSTDAGFHFAGDGR- 297  Caenorhabditis e...
P92163     202 EAPYGFKNVLPLNENTNLFSETVMNQRASGNLDAPEGGMDALMQITVCGNQIGWREn--ARHLVIYTTDSSS-IMPETK- 277  Strongylocentrot...
Q27591     205 EPTYGYRHQLSLTDDIPAFTSAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEq--ARKVVILVTDGFMHLAGDGL- 281  fruit fly
P91774     215 APPYSFRNDLPLDDDPKQFTIKVNEAPISGNMDSPEGGFDALMQVMVCTDQIGWREq--ARRIVIFSTDAKFHHAGDGR- 291  signal crayfish
CAL38675   205 LPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNd--SLHLLVFVSDADSHFGMDSK- 281  synthetic construct
NP_002205  219 MPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKe--AKRLLLVMTDQTSHLALDSK- 295  human
NP_524793  253 KAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREq--ARRLLVFSTDAGFHYAGDGK- 329  fruit fly
AAB66910   185 VATYGFKNVLPLVNDTVEFQTKINQQIISGNLDAPEGGFDALMQVAACEKEIGWSRngtSRRLVVFATDDSFHIAGDGK- 263  Acropora millepora
CAB61345   197 DPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPd--STHLLVFSTESAFHYEADGAn 274  human

1TYE_B     262 -LAGIVQPNDGQCHVGSDn-HYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVnLYQNYSELIP--GTTVGVLSMDS 337  human
Q27874     298 -LAGVVEPNDGTCHLDREg-YYTETLNQDYPSIALLHQMIKDRKANVIFAVTKNNQdLYTQLSNALPdvSSSVGVLANDS 375  Caenorhabditis e...
P92163     278 -LGGIITPNDGQCYLDPIsqNYTMSHYLDYPSIRHLNAKMRENSVIPIFAVIQKEFeIYNNLTQYIE--GATAGILAQDS 354  Strongylocentrot...
Q27591     282 -LAGIIQRNDKQCHLNKAg-EYTGSLNYDYPSLEEIYRELLRRKINVIFAVTEEVVsSYWELSALMKe-ISYVDILSADS 358  fruit fly
P91774     292 -LAGIVAPNDETCHLNNLq-EYTDFDKYDYPSIAQINKIAKEKNINVIFAVSSHEL-LYKELSGMIE--TSSYGMLDADS 366  signal crayfish
CAL38675   282 -LAGIVIPNDGLCHLDSKn-EYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVhLYENYAKLIP--GATVGLLQKDS 357  synthetic construct
NP_002205  296 -LAGIVVPNDGNCHLKNN--VYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFhWYKDLLPLLP--GTIAGEIESKA 370  human
NP_524793  330 -LGGVIAPNDGECHLSPKg-EYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLsVYEKLVEHIQ--GSSAAKLDNDS 405  fruit fly
AAB66910   264 -LGGIVTPNDGKCHLDSNg-YYTKSKDQDYPSIAHLHEKLQESNVLPIFAVTKQFAsLYKSVSTMWSdlGAVTGTLATDS 341  Acropora millepora
CAB61345   275 vLAGIMSRNDERCHLDTTg-TYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYsYYEKLHTYFP--VSSLGVLQEDS 351  human

1TYE_B     338 SNVLQLIVDAYGKIRSKVELEVRDL-PEELSLSFNA-TCLNNEVIPGL--K-SCMGLKIGDTVSFSIEAKVRGCP--QEk 410  human
Q27874     376 RNIVDLIEKEYLKISEKIIMVDNANaSEGLKLTYRS-MCLDGTTLKDT--N-VCEGIRVGDEVQFEVTLENTHCI--DKr 449  Caenorhabditis e...
P92163     355 NNIVQLVKDNYSKITSRVEVVDDA--PENVTIDYGP-HCPGGQVTPGS--Q-VCEGLQLGDTVNFTLTITATGCP--PNk 426  Strongylocentrot...
Q27591     359 SNILELIKKSYESLIKRTQFADNS--PDFIDMAYYT-DCGGQFPSLQK--RnYCNNVTLGKQIDFYVDVTLKKYP--DNq 431  fruit fly
P91774     367 GNVVELVRDQYNKISSTMRLTDNST-NSAVSVRYFS-SCKEGGAPVLT--R-ECGDIKENDTIDFLLEITAVECP--KD- 438  signal crayfish
CAL38675   358 GNILQLIISAYEELRSEVELEVLGD-TEGLNLSFTA-ICNNGTLFQHQ--K-KCSHMKVGDTASFSVTVNIPHC----Er 428  synthetic construct
NP_002205  371 ANLNNLVVEAYQKLISEVKVQVENQ-VQGIYFNITA-ICPDGSRKPGM--E-GCRNVTSNDEVLFNVTVTMKKCD--VTg 443  human
NP_524793  406 SNVVELVKEEYRKISSSVEMKDNA--TGDVKITYFS-SCLSNGPEVQT--S-KCDNLKEGQQVSFTAQIQLLKCPedPRd 479  fruit fly
AAB66910   342 DNVVELIKNKYEEIVSTVSLVYKE--PERVSVTVKA-NCGPNSVNTQT--R-MCSNVKLGQKVSFDVSVKLEGCP--TKd 413  Acropora millepora
CAB61345   352 SNIVELLEEAFNRIRSNLDIRALDS-PRGLRTEVTSkMFQKTRTGSFHirR-GEVGIYQVQLRALEHVDGTHVCQl-PEd 428  human

1TYE_B     411 ---EKSFTIKPVGFKD--SLIVQVTFDCDC 435  human
Q27874     450 ---DFVLRIGPSGLDE--TLIVNVKVLCDC 474  Caenorhabditis elegans
P92163     427 ---YQQFTVRP-LIQR--ELKVNVEFACDC 450  Strongylocentrotus purpuratus
Q27591     432 v-yTHKIRVEETSLSEfmDLDVELQRPCPC 460  fruit fly
P91774     439 ---ANTTYVEVKTLQD--NLVLEIEFKCSC 463  signal crayfish
CAL38675   429 --rSRHIIIKPVGLGD--ALELLVSPECNC 454  synthetic construct
NP_002205  444 --gKNYAIIKPIGFNE--TAKIHIHRNCSC 469  human
NP_524793  480 --wTQTIHISPVGINE--VMQIQLTMLCSC 505  fruit fly
AAB66910   414 adkAKSFVVRVPGFG---SVELELNYICQC 440  Acropora millepora
CAB61345   429 --qKGNIHLKP-SFSD--GLKMDAGIICDv 453  human