1GXE


Conserved Protein Domain Family
Ig_C5_MyBP-C

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cd05894: Ig_C5_MyBP-C (this model, PSSM-Id:143302 is obsolete and has been replaced by 409475)
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C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
Ig_C5_MyBP_C: the C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C). MyBP_C consists of repeated domains, Ig and fibronectin type 3, and various linkers. Three isoforms of MYBP_C exist and are included in this group: cardiac(c), and fast and slow skeletal muscle (s) MyBP_C. cMYBP_C has insertions between and inside domains and an additional cardiac-specific Ig domain at the N-terminus. For cMYBP_C an interaction has been demonstrated between this C5 domain and the Ig C8 domain.
Statistics
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PSSM-Id: 143302
Aligned: 5 rows
Threshold Bit Score: 134.206
Created: 11-Jan-2008
Updated: 18-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GXE_A         24 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQkaitqgnkaparpapdapedtgdsdewvfdkkllcetegrvRVETTKDRS 103  human
AAA49068      402 AENTIVVVAGNKVRLDVPISGEPAPTVTWKrgdqlft----------------------------ategrvHIDSQADLS 453  chicken
NP_001013529  515 SQNTIIVVAGNKLRLDVEITGEPAPTVCWMrddkpvt----------------------------dsegrvRVENKKDLS 566  zebrafish
Q14324        551 SENAIVVVAGNKLRLDVSITGEPPPVATWLkgdevft----------------------------ttegrtRIEKRVDCS 602  human
Q00872        531 ADNTVTVIAGNKLRLEIPISGEPPPKAMWSrgdkaim----------------------------egsgriRTESYPDSS 582  human
1GXE_A        104 IFTVeGAEKEDEGVYTVTVKNpVGEDQVNLTVKV 137  human
AAA49068      454 SFVIeSAERSDEGRYCITVTNpVGEDSATLHVRV 487  chicken
NP_001013529  567 CFIIeGAEREDEGNYTITVTNpAGEDKANLFIKI 600  zebrafish
Q14324        603 SFVIeSAQREDEGRYTIKVTNpVGEDVASIFLQV 636  human
Q00872        583 TLVIdIAERDDSGVYHINLKNeAGEAHASIKVKV 616  human
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